GLOXIMONAM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H25N5O8S
Molecular Weight	471.485
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CO\N=C(/C(=O)N[C@H]1[C@H](C)N(OCC(=O)OCC(=O)OC(C)(C)C)C1=O)C2=CSC(N)=N2

InChI

InChIKey=QPWVHJDIDXILDG-SSUKDTCJSA-N

InChI=1S/C18H25N5O8S/c1-9-13(21-15(26)14(22-28-5)10-8-32-17(19)20-10)16(27)23(9)30-7-11(24)29-6-12(25)31-18(2,3)4/h8-9,13H,6-7H2,1-5H3,(H2,19,20)(H,21,26)/b22-14-/t9-,13-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H25N5O8S
Molecular Weight	471.485
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3754552

Gloximonam (SQ-82531) is a beta-lactam antibiotic. This is a class of antibiotics that contains a beta-lactam ring in their molecular structure, such as penicillin derivatives. Gloximonam is orally absorbed and has shown anti-bacterial activity against different bacteria of the Enterobacteriaceae and Haemophilus influenzae families. Gloximonam is not effective against staphylococci and strict anaerobes (like aztreonam) and (unlike aztreonam) against Pseudomonas aeruginosa.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:17 GMT 2023` Edited by `admin` on `Fri Dec 15 15:11:17 GMT 2023`
Record UNII	9J68LNZ9ZL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLOXIMONAM

Official Name

English

SQ-82531

Code

English

gloximonam [INN]

Common Name

English

SQ 82531

Code

English

GLOXIMONAM [USAN]

Common Name

English

ACETIC ACID, ((3-(((2-AMINO-4-THIAZOLYL)(METHOXYIMINO)ACETYL)AMINO)-2-METHYL-4-OXO-1-AZETIDINYL)OXY)-, 2-(1,1-DIMETHYLETHOXY)-2-OXOETHYL ESTER, (2S-(2.ALPHA.,3.BETA.(Z)))-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C260