Hexedine has been used as an antimicrobial agent and drug constituent. Information about the current use of this drug is not available.

Flazalone is a nonsteroidal anti-inflammatory drug. In acute irritant anti-inflammatory tests, flazalone exhibited a wide spectrum of activity. The compound was active in affecting the course of paw swelling in adjuvant arthritis when given daily either at the outset of the polyarthritis or after induction. The most unusual aspect of this compound is its ability to inhibit graft rejection in goldfish and rabbits.

Intrazole (also known as BL-R743) is an indole derivative patented by Bristol-Myers Co and studied for Fungal infections treatment. In preclinical modes Intrazole shows anti-inflammatory activity in intact and adrenalectomized animals, employing the foot edema assay. Intrazole increased the antiinflammatory effect of hydrocortisone in the granuloma pouch model and effectively inhibited or alleviated adjuvant-induced polyarthritis.

Chloralose (alpha-Chloralose, 1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose) is an avicide, and a rodenticide commonly used for the control of mice and birds. Since its initial description in 1893, alpha-chloralose has undergone extensive pharmacologic evaluation. It has been characterized as a compound possessing potent CNS activity and has been evaluated in humans and animal models for its therapeutic properties. Though the toxicity of the compound prohibits its use as a human therapeutic agent, it has been employed widely as an animal anesthetic in the laboratory setting. α-Chloralose is widely used as an anesthetic in studies of the cerebrovasculature because of its presumed minimal depression of autonomic function. α-Chloralose acts as the positive allosteric modulator of GABA-A receptor and increases the affinity for GABA 5-fold and produced a small increase in the efficacy of GABA. Studies of α-Chloralose interactions with other allosteric modulators determined that α-Chloralose binds to a site on the GABAA receptor complex distinct from the benzodiazepine, neurosteroid and barbiturate sites.

Tibrofan is a non-peptide integrin αIIb/β3 receptor inhibitor and is usually used in combination with heparin to help prevent blood clotting.

Thyromedan is a thyroalkanoic acid derivative with hypocholesterolemic activity. In clinical trials, Thyromedan in daily doses of 8 to 32 mg caused a decrease in serum cholesterol levels. The serum total triglycerides and the α- and β-lipoprotein partition of cholesterol and triglycerides were unaffected.

Thyroxine I-131 is a radiolabeled thyroid hormone that has been studied as a diagnostic agent for thyroid cancer. In pharmacokinetic studies, Thyroxine I-131 shows broad tissue distribution and 99% of the ingested radiolabeled Thyroxine may be found in the skin, intestines, muscles, blood, bones, liver, and thyroid glands of rats.

Fiacitabine, also known as FIAC, is a pyrimidine nucleoside, which had been in phase II clinical trilas for the treatment Cytomegalovirus infections and Herpes simplex virus infections. However, these researches have been discontinued. It was also shown the inhibitor activity of FIAC against the DNA polymerase of hepadnaviruses.