Stereochemistry | UNKNOWN |
Molecular Formula | C19H19F2NO2 |
Molecular Weight | 331.3565 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CCC(O)(C(C1)C(=O)C2=CC=C(F)C=C2)C3=CC=C(F)C=C3
InChI
InChIKey=PPQZABOURJVKNI-UHFFFAOYSA-N
InChI=1S/C19H19F2NO2/c1-22-11-10-19(24,14-4-8-16(21)9-5-14)17(12-22)18(23)13-2-6-15(20)7-3-13/h2-9,17,24H,10-12H2,1H3
Flazalone is a nonsteroidal anti-inflammatory drug. In acute irritant anti-inflammatory tests, flazalone exhibited a wide spectrum of activity. The compound was active in affecting the course of paw swelling in adjuvant arthritis when given daily either at the outset of the polyarthritis or after induction. The most unusual aspect of this compound is its ability to inhibit graft rejection in goldfish and rabbits.