Class (Stereo):
CHEMICAL (ACHIRAL)
Dapansutrile is an inhibitor of the NLRP3 inflammasome, developed by Olatec Therapeutics LLC. NLRP3 inflammasome is a driver of sterile inflammation in response to myocardial ischemia-reperfusion and other inflammatory conditions. Dapansutrile limits...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Belnacasan (VX-765), and its active metabolite VRT- 043198, is a novel and irreversible IL-converting enzyme/ caspase-1 inhibitor. VRT-043198 exhibits 100- to 10,000-fold selectivity against other caspase-3, -6 and -9. It exhibited potent inhibition ...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated from various plants of the genus Andrographis, commonly known as 'creat'. Andrographolide has been tested for its anti-inflammatory effects in various stre...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Potassium tetrachloroplatinate is used in the preparation of platinum (Pt) nanoparticles. Ligands like ammonia or triphenyl phosphine can able to replace the chloride ligands to afford various derivatives. The replacement by ammonia results in the pr...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Menthone is a naturally occurring organic compound. It is found in oils of peppermint, Japanese mint, pennyroyal, Micromeria abyssinica benth, geranium and other oils. It is widely used as fragrances and flavors in the cosmetic, perfume, drug, and fo...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Gallium nitrate (brand name Ganite) is a drug that is used to treat hyper-calcemia, or too much calcium in the blood. Ganite exerts a hypocalcemic effect by inhibiting calcium resorption from bone, possibly by reducing increased bone turnover. It was...
Class (Stereo):
CHEMICAL (RACEMIC)
Monolaurin, derived naturally from coconut, is a source of the medium chain fatty acid lauric acid. Monolaurin has been widely researched for its antiviral, antibacterial, and antimicrobial properties, as it can break down and destroy the lipid layer...
Class (Stereo):
CHEMICAL (ACHIRAL)
Stearic monoethanolamide (widely known as N-stearoylethanolamine, NSE) is a biologically active cell membrane component with anti-inflammatory and membrane-protective properties. Preliminary data from a model of experimental burn in rats have shown t...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Romurtide (Muroctasin) is a non-specific immune stimulant derived from muramyl dipeptide, which is obtained from gram-positive bacterial cell walls. Muroctasin stimulates macrophages, which release interleukin-l, which in turn increases production of...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Iguratimod, a methanesulfonanilide, is an anti-inflammatory drug for the treatment of rheumatoid arthritis that has been developed exclusively in Japan and China. It inhibits the production of immunoglobulins and various inflammatory cytokines (inter...