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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
CH223191 is a ligand-selective antagonist of the aryl hydrocarbon (dioxin) receptor (AhR), a ligand-dependent transcription factor that produces a wide range of biological and toxic effects in many species and tissues.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
GW627368 is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor with additional human prostanoid TP receptor affinity. GW627368X effectively inhibits tumor survival, motility, proliferation and angiogenesis by blocking EP4-signaling. No major organ toxicity, immunosupression, behavioral change or change in blood parameters attributable to the drug was observed.
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
L-838,417 is a subtype-selective GABAA modulator, acting as a partial agonist at alpha2, alpha3 and alpha5 subtypes and an antagonist at the alpha1 subtype. L-838,417 displays anxiolytic effects in vivo and is used as a tool compound to study roles of GABAA subunits.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
