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Details

Stereochemistry RACEMIC
Molecular Formula C17H18BrNO
Molecular Weight 332.235
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SKF-83566

SMILES

CN1CCC2=C(C=C(O)C(Br)=C2)C(C1)C3=CC=CC=C3

InChI

InChIKey=XFTVOHWWEQGXLS-UHFFFAOYSA-N
InChI=1S/C17H18BrNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3

HIDE SMILES / InChI

Molecular Formula C17H18BrNO
Molecular Weight 332.235
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.51 µM [IC50]
PubMed

PubMed

TitleDatePubMed
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
1991 Apr 18
Mutual inhibitory effects between dopamine and carbachol on the excitatory synaptic transmission in the rat neostriatum.
1996 Oct 1
Effects of dopamine receptor antagonists on ongoing maternal behavior in rats.
2001 Mar
Effects of d-amphetamine and DOI (2,5-dimethoxy-4-iodoamphetamine) on timing behavior: interaction between D1 and 5-HT2A receptors.
2006 Dec
Evidence for the sensitivity of operant timing behaviour to stimulation of D1 dopamine receptors.
2007 Dec
Nanomolar propofol stimulates glutamate transmission to dopamine neurons: a possible mechanism of abuse potential?
2008 Apr
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:21:33 GMT 2023
Edited
by admin
on Sat Dec 16 08:21:33 GMT 2023
Record UNII
D203LR7XUS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SKF-83566
Common Name English
1H-3-BENZAZEPIN-7-OL, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-
Systematic Name English
SK&F 83566
Common Name English
1H-3-BENZAZEPIN-7-OL, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-, (±)-
Systematic Name English
SK&F-83566
Common Name English
Code System Code Type Description
FDA UNII
D203LR7XUS
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY
CAS
99295-33-7
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY
PUBCHEM
1243
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY
EPA CompTox
DTXSID8043816
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY