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Details

Stereochemistry RACEMIC
Molecular Formula C17H18BrNO
Molecular Weight 332.235
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SKF-83566

SMILES

CN1CCC2=CC(Br)=C(O)C=C2C(C1)C3=CC=CC=C3

InChI

InChIKey=XFTVOHWWEQGXLS-UHFFFAOYSA-N
InChI=1S/C17H18BrNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3

HIDE SMILES / InChI

Molecular Formula C17H18BrNO
Molecular Weight 332.235
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.51 µM [IC50]
PubMed

PubMed

TitleDatePubMed
Nanomolar propofol stimulates glutamate transmission to dopamine neurons: a possible mechanism of abuse potential?
2008-04
Evidence for the sensitivity of operant timing behaviour to stimulation of D1 dopamine receptors.
2007-12
Effects of d-amphetamine and DOI (2,5-dimethoxy-4-iodoamphetamine) on timing behavior: interaction between D1 and 5-HT2A receptors.
2006-12
Effects of dopamine receptor antagonists on ongoing maternal behavior in rats.
2001-03
Mutual inhibitory effects between dopamine and carbachol on the excitatory synaptic transmission in the rat neostriatum.
1996-10-01
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
1991-04-18
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:01:28 GMT 2025
Edited
by admin
on Mon Mar 31 22:01:28 GMT 2025
Record UNII
D203LR7XUS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SKF-83566
Common Name English
SK&F 83566
Preferred Name English
1H-3-BENZAZEPIN-7-OL, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-
Systematic Name English
1H-3-BENZAZEPIN-7-OL, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-, (±)-
Systematic Name English
SK&F-83566
Common Name English
Code System Code Type Description
FDA UNII
D203LR7XUS
Created by admin on Mon Mar 31 22:01:28 GMT 2025 , Edited by admin on Mon Mar 31 22:01:28 GMT 2025
PRIMARY
CAS
99295-33-7
Created by admin on Mon Mar 31 22:01:28 GMT 2025 , Edited by admin on Mon Mar 31 22:01:28 GMT 2025
PRIMARY
PUBCHEM
1243
Created by admin on Mon Mar 31 22:01:28 GMT 2025 , Edited by admin on Mon Mar 31 22:01:28 GMT 2025
PRIMARY
EPA CompTox
DTXSID8043816
Created by admin on Mon Mar 31 22:01:28 GMT 2025 , Edited by admin on Mon Mar 31 22:01:28 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY