Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C14H21N3O3 |
| Molecular Weight | 279.3348 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(C)NCC(O)COC1=C2NC(=O)NC2=CC=C1
InChI
InChIKey=UMQUQWCJKFOUGV-UHFFFAOYSA-N
InChI=1S/C14H21N3O3/c1-14(2,3)15-7-9(18)8-20-11-6-4-5-10-12(11)17-13(19)16-10/h4-6,9,15,18H,7-8H2,1-3H3,(H2,16,17,19)
| Molecular Formula | C14H21N3O3 |
| Molecular Weight | 279.3348 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Beta 3-adrenergic receptor-mediated lipolysis and oxygen consumption in brown adipocytes from cynomolgus monkeys. | 1997 Feb |
|
| Adrenergic stimulation of lipoprotein lipase gene expression in rat brown adipocytes differentiated in culture: mediation via beta3- and alpha1-adrenergic receptors. | 1997 Feb 1 |
|
| Effects of (-)-RO363 at human atrial beta-adrenoceptor subtypes, the human cloned beta 3-adrenoceptor and rodent intestinal beta 3-adrenoceptors. | 1997 Jan |
|
| A highly selective beta1-adrenergic blocker with partial beta2-agonist activity derived from ferulic acid, an active component of Ligusticum wallichii Franch. | 1998 May |
|
| LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors. | 1999 Feb 19 |
|
| Beta 1-adrenoceptor selectivity of nebivolol and bisoprolol. A comparison of [3H]CGP 12.177 and [125I]iodocyanopindolol binding studies. | 2003 Jan 26 |
|
| Agonist actions of "beta-blockers" provide evidence for two agonist activation sites or conformations of the human beta1-adrenoceptor. | 2003 Jun |
|
| Evaluation of beta-adrenergic receptor subtypes in the human prostate cancer cell line-LNCaP. | 2003 May 1 |
|
| Effects of growth hormone on the function of beta-adrenoceptor subtypes in rat adipocytes. | 2004 Feb |
|
| Recruitment of functionally active heart beta2-adrenoceptors in the initial phase of endotoxic shock in pithed rats. | 2006 Nov |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:02:58 GMT 2025
by
admin
on
Mon Mar 31 22:02:58 GMT 2025
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| Record UNII |
R89UMZ82MJ
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| Record Status |
Validated (UNII)
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| Record Version |
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R89UMZ82MJ
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DTXSID901001733
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2687
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81047-99-6
Created by
admin on Mon Mar 31 22:02:58 GMT 2025 , Edited by admin on Mon Mar 31 22:02:58 GMT 2025
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| Related Record | Type | Details | ||
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TARGET -> INHIBITOR |
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TARGET -> INHIBITOR |
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TARGET -> AGONIST |
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