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Details

Stereochemistry RACEMIC
Molecular Formula C17H18BrNO
Molecular Weight 332.235
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SKF-83566

SMILES

CN1CCC2=C(C=C(O)C(Br)=C2)C(C1)C3=CC=CC=C3

InChI

InChIKey=XFTVOHWWEQGXLS-UHFFFAOYSA-N
InChI=1S/C17H18BrNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.51 µM [IC50]
PubMed

PubMed

TitleDatePubMed
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
1991 Apr 18
Mutual inhibitory effects between dopamine and carbachol on the excitatory synaptic transmission in the rat neostriatum.
1996 Oct 1
Evidence for the sensitivity of operant timing behaviour to stimulation of D1 dopamine receptors.
2007 Dec
Nanomolar propofol stimulates glutamate transmission to dopamine neurons: a possible mechanism of abuse potential?
2008 Apr
Name Type Language
SKF-83566
Common Name English
1H-3-BENZAZEPIN-7-OL, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-
Systematic Name English
SK&F 83566
Common Name English
1H-3-BENZAZEPIN-7-OL, 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-, (±)-
Systematic Name English
SK&F-83566
Common Name English
Code System Code Type Description
FDA UNII
D203LR7XUS
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY
CAS
99295-33-7
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY
PUBCHEM
1243
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY
EPA CompTox
DTXSID8043816
Created by admin on Sat Dec 16 08:21:33 GMT 2023 , Edited by admin on Sat Dec 16 08:21:33 GMT 2023
PRIMARY