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Showing 1 - 10 of 22 results

Status:
US Approved Rx (2016)
First approved in 2003

Class (Stereo):
CHEMICAL (ABSOLUTE)



CRESTOR (rosuvastatin calcium) is an inhibitor of HMG-CoA reductase. It has been widely launched for the treatment of patients with dyslipidaemia and has also been approved in the US and EU to slow the progression of atherosclerosis.
Status:
US Approved Rx (2019)
First approved in 1999

Class (Stereo):
CHEMICAL (ABSOLUTE)



Sirolimus is the USAN-assigned generic name for the natural product rapamycin. Sirolimus is produced by a strain of Streptomyces hygroscopicus, isolated from a soil sample collected from Rapa Nui commonly known as Easter Island. Although sirolimus wa...
Status:
US Approved Rx (2010)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Aztreonam is the first monocyclic beta-lactam antibiotic (monobactam) originally isolated from Chromobacterium violaceum. Aztreonam has a high affinity for the protein-binding protein 3 (PBP-3) of aerobic gram-negative bacteria. Most of these organis...
Status:
US Approved Rx (2018)
First approved in 1959

Class (Stereo):
CHEMICAL (ABSOLUTE)



Oxymorphone is an analgesic that is FDA approved for the treatment of moderate to severe pain. It is also indicated for relief of anxiety in patients with dyspnea associated with pulmonary edema secondary to acute left ventricular dysfunction. Oxymor...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)


Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing...
Status:
US Previously Marketed
First approved in 2011

Class (Stereo):
CHEMICAL (EPIMERIC)



Boceprevir (trade name Victrelis) is first-generation, selective, small molecule inhibitor of the non-structural serine protease (NS3) and NS4A polypeptide complex (NS3/NS4A) and is a direct acting antiviral drug against the hepatitis C virus. It is ...
Status:
US Previously Marketed
First approved in 1995

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dirithromycin (Dynabac) is a macrolide glycopeptide antibiotic used to treat different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, skin infections. Dirithromycin is a semi-synthetic derivative of erythromycin - the hemi...
Status:
US Previously Marketed
First approved in 1993

Class (Stereo):
CHEMICAL (ABSOLUTE)



Levocabastine (trade name Livo) is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine binds the G protein-coupled neurotensin receptor 2 (NTR2), but not NTR1, where it behaves as a weak partial invers...
Status:
US Previously Marketed
First approved in 1963

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

A synthetic, carbanilide compound with antiseptic activity. Cloflucarban is used as disinfectant and is found in antimicrobial soaps and deodorants. Cloflucarban remains Category II as a health care antiseptic for use as a patient preoperative skin p...
Status:
US Approved Rx (2016)
First approved in 2003

Class (Stereo):
CHEMICAL (ABSOLUTE)



CRESTOR (rosuvastatin calcium) is an inhibitor of HMG-CoA reductase. It has been widely launched for the treatment of patients with dyslipidaemia and has also been approved in the US and EU to slow the progression of atherosclerosis.