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Showing 1 - 10 of 47 results

Status:
US Approved Rx (2020)
First approved in 2020

Class (Stereo):
CHEMICAL (ACHIRAL)



Bempedoic acid (also known as ETC-1002) is a novel investigational drug being developed for the treatment of dyslipidemia, hypercholesterolemia and other cardio-metabolic risk factors. The hypolipidemic, anti-atherosclerotic, anti-obesity, and glucos...
Status:
US Approved Rx (2016)
First approved in 2003

Class (Stereo):
CHEMICAL (ABSOLUTE)



CRESTOR (rosuvastatin calcium) is an inhibitor of HMG-CoA reductase. It has been widely launched for the treatment of patients with dyslipidaemia and has also been approved in the US and EU to slow the progression of atherosclerosis.
Status:
US Approved Rx (2012)
First approved in 1993

Class (Stereo):
CHEMICAL (RACEMIC)



Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Fluvastatin is marketed under the trade names Lescol, Canef, Vastin. LESCOL/LESCOL XL is an HMG-CoA reductase inhibitor (statin) ind...
Status:
US Approved Rx (2012)
First approved in 1993

Class (Stereo):
CHEMICAL (ACHIRAL)



Fenofibrate is a drug of the fibrate class. It is mainly used to reduce cholesterol levels in people at risk of cardiovascular disease. It’s used as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase...
Status:
US Approved Rx (2006)
First approved in 1991

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease. Pravastatin acts as a lipoprotein-lowe...
Status:
US Approved Rx (2001)
First approved in 1987

Class (Stereo):
CHEMICAL (ABSOLUTE)



Lovastatin acid is an active metabolite of hypolipidemic drug Lovastatin. Lovastatin acid inhibits HMG-CoA reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate limiting step in the biosynthesis of chole...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Secoisolariciresinol diglucoside (SDG) isolated from flaxseed is a lipid-lowering and antioxidant agent. It suppresses the development of hypercholesterolemic atherosclerosis in rabbits. Secoisolariciresinol diglucoside has been shown to have antioxi...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Anacetrapib is a CETP inhibitor being developed by Merck to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Anacetrapib is a cholesterol ester transfer protein (CETP) inhibitor that blocks the transfer of ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)


Tizoprolic acid is an anti-lipolytic drug, a blood ketone lowering agent.
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Torcetrapib is a CETP inhibitor which was developed by Pfizer for the treatment of diseases associated with elevated level of cholesterol. The drug was tested in phase III (in combination with atorvastatin) of clinical trials in coronary heart diseas...