TIZOPROLIC ACID

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9NO2S
Molecular Weight	171.217
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TIZOPROLIC ACID

Structure Search

SMILES

CCCC1=NC=C(S1)C(O)=O

InChI

InChIKey=IOSZDNOGOPHEPH-UHFFFAOYSA-N

InChI=1S/C7H9NO2S/c1-2-3-6-8-4-5(11-6)7(9)10/h4H,2-3H2,1H3,(H,9,10)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7467395 | https://www.ncbi.nlm.nih.gov/pubmed/417186

Tizoprolic acid is an anti-lipolytic drug, a blood ketone lowering agent.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Hypercholesterolemia 51 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7467395	Primary		Basic research	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
The metabolic fate of tizoprolique acid in baboons.	1980-11	7467395
Effect of diabetic ketosis on enzyme release from isolated perfused rat hearts with experimental myocardial infarction.	1978-03	417186

Patents

Patents

Sample Use Guides

In Vivo Use Guide

After oral administration of [14C]tizoprolic acid to baboons (60 mg/kg), the radioactivity was well absorbed and rapidly excreted.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

tizoprolic acid [INN]

Preferred Name

English

TIZOPROLIC ACID

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29703

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Code System Code Type Description

MESH

C016789

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ChEMBL

CHEMBL2106500

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CAS

30709-69-4

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NCI_THESAURUS

C75261

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EPA CompTox

DTXSID5057709

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FDA UNII

VGT0G37N5M

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SMS_ID

100000082124

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EVMPD

SUB11131MIG

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PUBCHEM

65773

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INN

3870

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ACTIVE MOIETY


					VGT0G37N5M

TIZOPROLIC ACID