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Details

Stereochemistry ACHIRAL
Molecular Formula C7H9NO2S
Molecular Weight 171.217
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIZOPROLIC ACID

SMILES

CCCC1=NC=C(S1)C(O)=O

InChI

InChIKey=IOSZDNOGOPHEPH-UHFFFAOYSA-N
InChI=1S/C7H9NO2S/c1-2-3-6-8-4-5(11-6)7(9)10/h4H,2-3H2,1H3,(H,9,10)

HIDE SMILES / InChI
Molecular Formula C7H9NO2S
Molecular Weight 171.217
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tizoprolic acid is an anti-lipolytic drug, a blood ketone lowering agent.

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effect of diabetic ketosis on enzyme release from isolated perfused rat hearts with experimental myocardial infarction.
1978 Mar
The metabolic fate of tizoprolique acid in baboons.
1980 Nov
Patents

Patents

US20110159073
3
WO2007061529A1
72

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Mice: LD50 = 1680 mg/kg, i.p. https://www.chemsrc.com/en/cas/30709-69-4_336492.html
After oral administration of [14C]tizoprolic acid to baboons (60 mg/kg), the radioactivity was well absorbed and rapidly excreted.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:12:21 GMT 2023
Edited
by admin
on Fri Dec 15 16:12:21 GMT 2023
Record UNII
VGT0G37N5M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TIZOPROLIC ACID
INN  
INN  
Official Name English
tizoprolic acid [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29703
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
Code System Code Type Description
MESH
C016789
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
ChEMBL
CHEMBL2106500
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
CAS
30709-69-4
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
NCI_THESAURUS
C75261
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
EPA CompTox
DTXSID5057709
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
FDA UNII
VGT0G37N5M
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
SMS_ID
100000082124
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
EVMPD
SUB11131MIG
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
PUBCHEM
65773
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
INN
3870
Created by admin on Fri Dec 15 16:12:21 GMT 2023 , Edited by admin on Fri Dec 15 16:12:21 GMT 2023
PRIMARY
Related Record Type Details
Structure of TIZOPROLIC ACID
ACTIVE MOIETY
NIH
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