Inxight Drugs

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Development Status

Investigational

6

Possibly Marketed Outside US

2

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Primary Target

Oxidative Stress

2

apoptotic process

2

cell proliferation

2

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Approval Year

Unknown

6

2010

2

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Condition

Hepatic encephalopathy

2

Stroke

2

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Treatment Modality

Primary

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CNS Activity

CNS Active

2

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Originator

Schulze, E.|Bosshard, E.

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Substance Class

Chemical

8

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CAS

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FDA UNII

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PUBCHEM

8

EPA CompTox

5

SMS_ID

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Substance Form

Salts, Hydrates, Esters, etc.

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Principal Form

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Showing 1 - 8 of 8 results

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INOSINIC ACID

TAO7US05G5

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

GUANOSINE

12133JR80S

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Status:

Possibly Marketed Outside US

First approved in 2010

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

cell proliferation

apoptotic process

Oxidative Stress

Conditions:

Hepatic encephalopathy

Guanosine is an endogenous guanine nucleoside. Guanosine was shown to be protective in several in vitro and/or in vivo experimental models of central nervous system (CNS) diseases including ischemic stroke, Alzheimer's disease, Parkinson's disease, s...

pinal cord injury, nociception, and depression. The mechanisms underlying the neurobiological properties of guanosine seem to involve the activation of several intracellular signaling pathways and a close interaction with the adenosinergic system, with a consequent stimulation of neuroprotective and regenerative processes in the CNS. Several guanosine analogues, i.e. acyclovir (and its oral prodrug valaciclovir), penciclovir (in its oral prodrug form, famciclovir) and ganciclovir, are widely used for the treatment of herpesvirus (i.e. HSV-1, HSV-2, VZV and HCMV) infections.

DISODIUM 5'-INOSINATE OCTAHYDRATE

30I0YM7F4V

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

DISODIUM 5'-INOSINATE MONOHYDRATE

KZ6R6P2Y0B

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

DISODIUM 5'-INOSINATE DIHYDRATE

B37782955L

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

DIPOTASSIUM 5'-INOSINATE

3BYM6LW3RF

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

DISODIUM 5'-INOSINATE

T2ZYA7KC05

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

GUANOSINE DIHYDRATE

E62RXW39EW

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Status:

Possibly Marketed Outside US

First approved in 2010

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

cell proliferation

apoptotic process

Oxidative Stress

Conditions:

Hepatic encephalopathy

Guanosine is an endogenous guanine nucleoside. Guanosine was shown to be protective in several in vitro and/or in vivo experimental models of central nervous system (CNS) diseases including ischemic stroke, Alzheimer's disease, Parkinson's disease, s...

pinal cord injury, nociception, and depression. The mechanisms underlying the neurobiological properties of guanosine seem to involve the activation of several intracellular signaling pathways and a close interaction with the adenosinergic system, with a consequent stimulation of neuroprotective and regenerative processes in the CNS. Several guanosine analogues, i.e. acyclovir (and its oral prodrug valaciclovir), penciclovir (in its oral prodrug form, famciclovir) and ganciclovir, are widely used for the treatment of herpesvirus (i.e. HSV-1, HSV-2, VZV and HCMV) infections.

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