Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H11N4O8P.2Na.8H2O |
| Molecular Weight | 536.2919 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.O.O.O.O.O.O.O.[Na+].[Na+].O[C@@H]1[C@@H](COP([O-])([O-])=O)O[C@H]([C@@H]1O)N2C=NC3=C2N=CNC3=O
InChI
InChIKey=QKWLBOYKTJDMLH-NAGQJCCQSA-L
InChI=1S/C10H13N4O8P.2Na.8H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;;;;;;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;8*1H2/q;2*+1;;;;;;;;/p-2/t4-,6-,7-,10-;;;;;;;;;;/m1........../s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Acid phosphatase/phosphotransferases from enteric bacteria. | 2001 |
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| Ageing and immunosuppression in kidney transplantation. | 2004 Dec |
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| Interferon: ten stories in one. A short review of some of the highlights in the history of an almost quinquagenarian. | 2005 |
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| Mechanisms of action of mycophenolate mofetil. | 2005 |
|
| Polyinosinic acid induces TNF and NO production as well as NF-kappaB and AP-1 transcriptional activation in the monocytemacrophage cell line RAW 264.7. | 2005 Aug |
|
| Stoichiometric estimates of the biochemical conversion efficiencies in tsetse metabolism. | 2005 Aug 5 |
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| Creatine supplementation reduces muscle inosine monophosphate during endurance exercise in humans. | 2005 Dec |
|
| Study of the reactions between platinum(II) complexes and L-methionine in the presence and absence of 5'-GMP. | 2005 Jul |
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| Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus. | 2005 Jun |
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| Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes. | 2005 Mar 18 |
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| Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence. | 2005 May 4 |
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| Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition. | 2005 May 9 |
|
| Competitive reactions of L-methionine and 5'-GMP towards platinum (II) complexes. | 2005 Nov |
|
| [Genetic parameter estimation for inosine-5-monophosphate and intramuscular fat contents and other meat quality traits in chicken muscle]. | 2005 Nov |
|
| Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection. | 2005 Oct 15 |
|
| Indications of mycophenolate mofetil in liver transplantation. | 2005 Sep 27 |
|
| Evaluation of immunomodulators, interferons and known in vitro SARS-coV inhibitors for inhibition of SARS-coV replication in BALB/c mice. | 2006 |
|
| Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer. | 2006 Apr 1 |
|
| The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats. | 2006 Feb 15 |
|
| Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis. | 2006 Jun 21 |
|
| Why do mutations in the ubiquitously expressed housekeeping gene IMPDH1 cause retina-specific photoreceptor degeneration? | 2006 Sep |
|
| Effect of exogenous interferon and an interferon inducer on western equine encephalitis virus disease in a hamster model. | 2007 Apr 10 |
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| TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules. | 2007 Apr 15 |
|
| Sources of umami taste in Cheddar and Swiss cheeses. | 2007 Aug |
|
| Correlation between breakdown of the blood-brain barrier and disease outcome of viral encephalitis in mice. | 2007 Aug |
|
| Formamide as the main building block in the origin of nucleic acids. | 2007 Aug 16 |
|
| Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor. | 2007 Feb 1 |
|
| Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes. | 2007 Jul |
|
| Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419). | 2007 Jul 26 |
|
| Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. | 2007 Jun 26 |
|
| Cross-protection against H5N1 influenza virus infection is afforded by intranasal inoculation with seasonal trivalent inactivated influenza vaccine. | 2007 Nov 1 |
|
| IMPDH1 promoter mutations in a patient exhibiting azathioprine resistance. | 2007 Oct |
|
| A motif-based search in bacterial genomes identifies the ortholog of the small RNA Yfr1 in all lineages of cyanobacteria. | 2007 Oct 17 |
|
| Characterization of retinal inosine monophosphate dehydrogenase 1 in several mammalian species. | 2007 Oct 3 |
|
| Intranasal immunization with H5N1 vaccine plus Poly I:Poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge. | 2007 Sep |
|
| The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation. | 2008 |
|
| The plasma ammonia response to cycle exercise in COPD. | 2008 Apr |
|
| Kinetic studies on the reactions of [Pd(dach)(X-Y)] complexes with some DNA constituents. | 2008 Feb 14 |
|
| Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis. | 2008 Jan |
|
| IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations. | 2008 Jan |
|
| Effects of dietary inosinic acid on carcass characteristics, meat quality, and deposition of inosinic acid in broilers. | 2008 Jul |
|
| Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes. | 2008 Jul |
|
| Estimation of genetic parameters for contents of intramuscular fat and inosine-5'-monophosphate and carcass traits in Chinese Beijing-You chickens. | 2008 Jun |
|
| C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection. | 2008 Jun |
|
| Expression of caffeine biosynthesis genes in tea (Camellia sinensis). | 2008 Mar-Apr |
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| Multiple receptor systems for glutamate detection in the taste organ. | 2008 Oct |
|
| Identification and characterization of two trypanosome TFIIS proteins exhibiting particular domain architectures and differential nuclear localizations. | 2008 Sep |
|
| Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3. | 2008 Sep |
|
| Predicting the sensitivity and specificity of published real-time PCR assays. | 2008 Sep 25 |
|
| A clinical grade poly I:C-analogue (Ampligen) promotes optimal DC maturation and Th1-type T cell responses of healthy donors and cancer patients in vitro. | 2009 Jan 1 |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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21107-91-5
Created by
admin on Sat Dec 16 09:44:29 GMT 2023 , Edited by admin on Sat Dec 16 09:44:29 GMT 2023
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ALTERNATIVE | |||
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352195-40-5
Created by
admin on Sat Dec 16 09:44:29 GMT 2023 , Edited by admin on Sat Dec 16 09:44:29 GMT 2023
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NON-SPECIFIC STOICHIOMETRY | |||
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135565914
Created by
admin on Sat Dec 16 09:44:29 GMT 2023 , Edited by admin on Sat Dec 16 09:44:29 GMT 2023
|
PRIMARY | |||
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20813-76-7
Created by
admin on Sat Dec 16 09:44:29 GMT 2023 , Edited by admin on Sat Dec 16 09:44:29 GMT 2023
|
PRIMARY | |||
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30I0YM7F4V
Created by
admin on Sat Dec 16 09:44:29 GMT 2023 , Edited by admin on Sat Dec 16 09:44:29 GMT 2023
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PRIMARY |
SUBSTANCE RECORD
