U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Showing 1 - 10 of 13 results

Status:
US Approved Rx (2015)
First approved in 2015

Class (Stereo):
CHEMICAL (ABSOLUTE)



Uridine triacetate (formally PN401) is an acetylated prodrug of uridine. Following oral administration, uridine triacetate is deacetylated by nonspecific esterases present throughout the body, yielding uridine in the circulation. Uridine triacetate u...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cytidine is a substrate of the uridine-cytidine kinase and is a part nucleic acids. It can serve as a substrate for the salvage pathway of pyrimidine nucleotide synthesis, as a precursor of the cytidine triphosphate (CTP) needed in the phosphatidylch...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
First approved in 2010

Class (Stereo):
CHEMICAL (ABSOLUTE)



Guanosine is an endogenous guanine nucleoside. Guanosine was shown to be protective in several in vitro and/or in vivo experimental models of central nervous system (CNS) diseases including ischemic stroke, Alzheimer's disease, Parkinson's disease, s...
Status:
US Approved Rx (2015)
First approved in 2015

Class (Stereo):
CHEMICAL (ABSOLUTE)



Uridine triacetate (formally PN401) is an acetylated prodrug of uridine. Following oral administration, uridine triacetate is deacetylated by nonspecific esterases present throughout the body, yielding uridine in the circulation. Uridine triacetate u...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Showing 1 - 10 of 13 results