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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H11N4O8P.2Na.H2O
Molecular Weight 410.1849
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISODIUM 5'-INOSINATE MONOHYDRATE

SMILES

O.[Na+].[Na+].O[C@@H]1[C@@H](COP([O-])([O-])=O)O[C@H]([C@@H]1O)N2C=NC3=C2N=CNC3=O

InChI

InChIKey=KQCIGEIXDXQSGM-MSQVLRTGSA-L
InChI=1S/C10H13N4O8P.2Na.H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Comparison of Al-induced gene expression in sensitive and tolerant soybean cultivars.
2003 Dec
Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice.
2003 Dec 21
Molecular signatures in protein sequences that are characteristic of cyanobacteria and plastid homologues.
2003 Nov
Inhibition of caffeine biosynthesis in tea (Camellia sinensis) and coffee (Coffea arabica) plants by ribavirin.
2003 Nov 20
Behavioral evidence for a role of alpha-gustducin in glutamate taste.
2003 Sep
Pickles, pectin, and penicillin.
2004
Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species.
2004
Mismatched double-stranded RNA: polyI:polyC12U.
2004
Ageing and immunosuppression in kidney transplantation.
2004 Dec
Nucleic acid synthesis in cancerous cells under the effect of gnidilatimonoein from Daphne mucronata.
2004 Feb 27
Substitution reactions of [Pt(terpy)X]2+ with some biologically relevant ligands. Synthesis and crystal structure of [Pt(terpy)(cyst-S)](ClO4)2.0.5H2O and [Pt(terpy)(guo-N7)](ClO4)2.0.5guo.1.5H2O.
2004 Jan 21
[Isolation of rice genes down-regulated by brown planthopper infestation by suppression subtractive hybridization].
2004 Jun
Effect of interferon-alpha and interferon-inducers on West Nile virus in mouse and hamster animal models.
2004 Mar
Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines.
2004 Mar 1
Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor.
2004 May 31
An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.
2004 Nov
Gustatory neural responses to umami taste stimuli in C57BL/6ByJ and 129P3/J mice.
2004 Nov
Equilibrium, kinetic and HPLC study of the reactions between platinum(II) complexes and DNA constituents in the presence and absence of glutathione.
2004 Nov 21
Overproduction of NAD+ and 5'-inosine monophosphate in the presence of 10 microM Mn2+ by a mutant of Corynebacterium ammoniagenes with thermosensitive nucleotide reduction (nrd(ts)) after temperature shift.
2004 Oct
Genome wide analysis of common and specific stress responses in adult drosophila melanogaster.
2004 Sep 30
Mechanisms of action of mycophenolate mofetil.
2005
Fast and systematic genome-wide discovery of conserved regulatory elements using a non-alignment based approach.
2005
Stoichiometric estimates of the biochemical conversion efficiencies in tsetse metabolism.
2005 Aug 5
Study of the reactions between platinum(II) complexes and L-methionine in the presence and absence of 5'-GMP.
2005 Jul
Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus.
2005 Jun
Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes.
2005 Mar 18
Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence.
2005 May 4
Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition.
2005 May 9
Competitive reactions of L-methionine and 5'-GMP towards platinum (II) complexes.
2005 Nov
Evaluation of immunomodulators, interferons and known in vitro SARS-coV inhibitors for inhibition of SARS-coV replication in BALB/c mice.
2006
Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer.
2006 Apr 1
The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats.
2006 Feb 15
Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.
2006 Jun 21
Effect of exogenous interferon and an interferon inducer on western equine encephalitis virus disease in a hamster model.
2007 Apr 10
TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules.
2007 Apr 15
Sources of umami taste in Cheddar and Swiss cheeses.
2007 Aug
Correlation between breakdown of the blood-brain barrier and disease outcome of viral encephalitis in mice.
2007 Aug
Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor.
2007 Feb 1
Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes.
2007 Jul
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).
2007 Jul 26
Cross-protection against H5N1 influenza virus infection is afforded by intranasal inoculation with seasonal trivalent inactivated influenza vaccine.
2007 Nov 1
A motif-based search in bacterial genomes identifies the ortholog of the small RNA Yfr1 in all lineages of cyanobacteria.
2007 Oct 17
Characterization of retinal inosine monophosphate dehydrogenase 1 in several mammalian species.
2007 Oct 3
The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation.
2008
Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis.
2008 Jan
Effects of dietary inosinic acid on carcass characteristics, meat quality, and deposition of inosinic acid in broilers.
2008 Jul
Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes.
2008 Jul
Expression of caffeine biosynthesis genes in tea (Camellia sinensis).
2008 Mar-Apr
Identification and characterization of two trypanosome TFIIS proteins exhibiting particular domain architectures and differential nuclear localizations.
2008 Sep
Predicting the sensitivity and specificity of published real-time PCR assays.
2008 Sep 25
Patents
Name Type Language
DISODIUM 5'-INOSINATE MONOHYDRATE
Common Name English
INOSINE 5'-PHOSPHATE DISODIUM MONOHYDRATE
Systematic Name English
5'-INOSINIC ACID, SODIUM SALT, HYDRATE (1:2:1)
Systematic Name English
Code System Code Type Description
CAS
1192013-78-7
Created by admin on Sat Dec 16 09:36:58 GMT 2023 , Edited by admin on Sat Dec 16 09:36:58 GMT 2023
PRIMARY
PUBCHEM
135565601
Created by admin on Sat Dec 16 09:36:58 GMT 2023 , Edited by admin on Sat Dec 16 09:36:58 GMT 2023
PRIMARY
CAS
352195-40-5
Created by admin on Sat Dec 16 09:36:58 GMT 2023 , Edited by admin on Sat Dec 16 09:36:58 GMT 2023
NON-SPECIFIC STOICHIOMETRY
FDA UNII
KZ6R6P2Y0B
Created by admin on Sat Dec 16 09:36:58 GMT 2023 , Edited by admin on Sat Dec 16 09:36:58 GMT 2023
PRIMARY