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Showing 1 - 10 of 18 results

Status:
US Approved Rx (2013)
First approved in 2010

Class (Stereo):
CHEMICAL (ACHIRAL)



Polidocanol is a non-ionic surfactant sclerosing agent indicated to treat uncomplicated spider veins and uncomplicated reticular veins in the lower extremity. Polidocanol also is indicated for the treatment of incompetent great saphenous veins, acces...
Status:
US Approved Rx (2024)
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Methylene blue, also known as methylthioninium chloride, is a medication from WHO's list of essential medicines. Upon administration, methylene blue is converted to leukomethylene blue by erythrocyte methemoblobin reductase in the presence of NADPH. ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Elinafide (LU 79553) is a bisintercalating naphthalamide and a topoisomerase II inhibitor has demonstrated a higher binding affinity for DNA and significant antitumour efficacy against a panel of established tumour cell lines, including several multi...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Cemadotin (LU103793) is a cytotoxic water-soluble pentapeptide analogue of dolastatin 15. The dolastatin peptides were originally isolated from the shell-less mollusc Dolabella auricularia. Cemadotin blocks cells at mitosis. It exerts its antitumor a...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Darusentan is an orally active, propanoic acid-based endothelin receptor antagonist (ERA) that selectively blocks endothelin-1 (ET-1) binding to the endothelin type-A (ETA) receptor. Darusentan exhibited subnanomolar binding affinity and approximatel...
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Triticonazole is a triazole pesticide/fungicide with broad antifungal activity. Like many azole fungicides, triticonazole likely inhibits 14-α demethylase, inhibiting ergosterol production and fungal cell wall synthesis. Additionally, triticonazole m...
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Nitrothal-isopropyl is a fungicide, used, usually in combination with other fungicides, to control fungal pathogens on a variety of crops including fruit and vegetables. Nitrothal-isopropyl is registered for use in South Africa, Australia and New Zea...
Status:
Possibly Marketed Outside US
First approved in 2012

Class (Stereo):
CHEMICAL (MIXED)


Ethylhexyl triazone is a PABA-derivative used in sunscreens to absorb UVB radiation. It is marketed as Uvinul T 150 by BASF. Ethylhexyl triazone has an absorption maximum of 314 nm. Ethylhexyl triazone is not approved as an active ingredient in the U...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Boscalid is a new pesticide belonging to the class of oxathiin fungicides, also known as carboxamide, carboxin or (carbox) anilide fungicides. U.S. EPA has designated the proposed uses of boscalid as “reduced risk.” Boscalid works by inhibiting mitro...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Topramezone is a pyrazolone herbicide developed by BASF, which is also an HPPD inhibitor, being effective for the control of weeds, which are resistant to glyphosate, triazines, ALS inhibitors and the ACCase inhibitors. Topramezone has a good control...

Showing 1 - 10 of 18 results