U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C18H12Cl2N2O
Molecular Weight 343.207
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BOSCALID

SMILES

ClC1=CC=C(C=C1)C2=C(NC(=O)C3=CC=CN=C3Cl)C=CC=C2

InChI

InChIKey=WYEMLYFITZORAB-UHFFFAOYSA-N
InChI=1S/C18H12Cl2N2O/c19-13-9-7-12(8-10-13)14-4-1-2-6-16(14)22-18(23)15-5-3-11-21-17(15)20/h1-11H,(H,22,23)

HIDE SMILES / InChI

Molecular Formula C18H12Cl2N2O
Molecular Weight 343.207
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Boscalid is a new pesticide belonging to the class of oxathiin fungicides, also known as carboxamide, carboxin or (carbox) anilide fungicides. U.S. EPA has designated the proposed uses of boscalid as “reduced risk.” Boscalid works by inhibiting mitrochondial respiration and subsequent production of ATP in fungal cells. Boscalid has a new mode of action and is effective against pathogens resistant to other fungicides, including those resistant to sterol inhibitors, dicarboximides, benzimidazoles, anilinopyrimidines, phenylamides and strobilurins.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Use of PRZM-3 to validate a laboratory to field degradation conceptual model.
2004 Jan
Developing an ecotoxicological testing standard for predatory mites in Australia: acute and sublethal effects of fungicides on Euseius victoriensis and Galendromus occidentalis (Acarina: Phytoseiidae).
2004 Jun
Signum, a new fungicide for control of leaf diseases in outdoor vegetables.
2005
Diagnostic tools to identify black aspergilli.
2007
Characterization of mutations in the iron-sulphur subunit of succinate dehydrogenase correlating with Boscalid resistance in Alternaria alternata from California pistachio.
2008 Jun
Palladium-catalyzed direct arylation of nitro-substituted aromatics with aryl halides.
2008 Oct 16
Colony collapse disorder: a descriptive study.
2009 Aug 3
Toxicity of six novel fungicides and sulphur to Galendromus occidentalis (Acari: Phytoseiidae).
2009 Jan
Effectiveness of control strategies against Botrytis cinerea in vineyard and evaluation of the residual fungicide concentrations.
2009 May
Residue analysis of kresoxim-methyl and boscalid in fruits, vegetables and soil using liquid-liquid extraction and gas chromatography-mass spectrometry.
2010 Apr
Minor crops for export: a case study of boscalid, pyraclostrobin, lufenuron and lambda-cyhalothrin residue levels on green beans and spring onions in Egypt.
2010 Aug
Dissipation and residues of boscalid in strawberries and soils.
2010 Mar
Response surface optimization for determination of pesticide residues in grapes using MSPD and GC-MS: assessment of global uncertainty.
2010 Oct
Multiple resistance of Botrytis cinerea from kiwifruit to SDHIs, QoIs and fungicides of other chemical groups.
2010 Sep
Effects of Common Pesticides on Prostaglandin D2 (PGD2) Inhibition in SC5 Mouse Sertoli Cells, Evidence of Binding at the COX-2 Active Site, and Implications for Endocrine Disruption.
2016 Apr
Patents

Sample Use Guides

Oral: LD50 Species: rat (male/female) Value: > 2,000 mg/kg
Route of Administration: Oral
Boscalid exhibited the potent antifungal effect on R. solani with an EC50 value of 1.758 mg/L.
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:45:26 GMT 2023
Edited
by admin
on Fri Dec 15 18:45:26 GMT 2023
Record UNII
32MS8ZRD1V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BOSCALID
HSDB   ISO   MI  
Common Name English
BAS 510 F
Code English
BOSCALID [MI]
Common Name English
BOSCALID [ISO]
Common Name English
EMERALD
INCI  
INCI  
Official Name English
ENDURA
Brand Name English
EMERALD [INCI]
Common Name English
BAS-510
Common Name English
NICOBIFEN
Common Name English
BOSCALID [HSDB]
Common Name English
2-CHLORO-N-(4'-CHLOROBIPHENYL-2-YL)NICOTINAMIDE
Systematic Name English
2-CHLORO-N-(4'-CHLORO(1,1'-BIPHENYL)-2-YL)-3-PYRIDINECARBOXAMIDE
Systematic Name English
BAS 510
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 128008
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
Code System Code Type Description
RXCUI
1735163
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
PRIMARY
CHEBI
81822
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
PRIMARY
CAS
188425-85-6
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
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EPA CompTox
DTXSID6034392
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
PRIMARY
PUBCHEM
213013
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
PRIMARY
HSDB
7499
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
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FDA UNII
32MS8ZRD1V
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
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MESH
C550088
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
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ALANWOOD
boscalid
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
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DAILYMED
32MS8ZRD1V
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
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DRUG BANK
DB12792
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
PRIMARY
MERCK INDEX
m2624
Created by admin on Fri Dec 15 18:45:26 GMT 2023 , Edited by admin on Fri Dec 15 18:45:26 GMT 2023
PRIMARY Merck Index