BOSCALID

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H12Cl2N2O
Molecular Weight	343.207
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(C=C1)C2=CC=CC=C2NC(=O)C3=CC=CN=C3Cl

InChI

InChIKey=WYEMLYFITZORAB-UHFFFAOYSA-N

InChI=1S/C18H12Cl2N2O/c19-13-9-7-12(8-10-13)14-4-1-2-6-16(14)22-18(23)15-5-3-11-21-17(15)20/h1-11H,(H,22,23)

HIDE SMILES / InChI

Molecular Formula	C18H12Cl2N2O
Molecular Weight	343.207
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.cdpr.ca.gov/docs/registration/ais/publicreports/5790.pdf | https://www.researchgate.net/publication/274379421_Mode_of_action_biological_performance_and_latest_monitoring_results_of_boscalid_sensitvity

Boscalid is a new pesticide belonging to the class of oxathiin fungicides, also known as carboxamide, carboxin or (carbox) anilide fungicides. U.S. EPA has designated the proposed uses of boscalid as “reduced risk.” Boscalid works by inhibiting mitrochondial respiration and subsequent production of ATP in fungal cells. Boscalid has a new mode of action and is effective against pathogens resistant to other fungicides, including those resistant to sterol inhibitors, dicarboximides, benzimidazoles, anilinopyrimidines, phenylamides and strobilurins.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
succinate dehydrogenase activity 3 Target ID: GO:0000104 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28482975 \| https://www.ncbi.nlm.nih.gov/pubmed/23901829 \| https://www.ncbi.nlm.nih.gov/pubmed/28622596	Inhibitor 8504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Effects of Common Pesticides on Prostaglandin D2 (PGD2) Inhibition in SC5 Mouse Sertoli Cells, Evidence of Binding at the COX-2 Active Site, and Implications for Endocrine Disruption.	2016-04	26359731
Response surface optimization for determination of pesticide residues in grapes using MSPD and GC-MS: assessment of global uncertainty.	2010-10	20694812
Multiple resistance of Botrytis cinerea from kiwifruit to SDHIs, QoIs and fungicides of other chemical groups.	2010-09	20730988
Minor crops for export: a case study of boscalid, pyraclostrobin, lufenuron and lambda-cyhalothrin residue levels on green beans and spring onions in Egypt.	2010-08	20574869
Residue analysis of kresoxim-methyl and boscalid in fruits, vegetables and soil using liquid-liquid extraction and gas chromatography-mass spectrometry.	2010-04	19650146
High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health.	2010-03-19	20333298
Residue analysis of multi-class pesticides in watermelon by LC-MS/MS.	2010-03	20175086
Dissipation and residues of boscalid in strawberries and soils.	2010-03	20111950
Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea.	2009-12	20019793
Multiresidue determination of 11 new fungicides in grapes and wines by liquid-liquid extraction/clean-up and programmable temperature vaporization injection with analyte protectants/gas chromatography/ion trap mass spectrometry.	2009-08-07	19576591
Colony collapse disorder: a descriptive study.	2009-08-03	19649264
Effectiveness of control strategies against Botrytis cinerea in vineyard and evaluation of the residual fungicide concentrations.	2009-05	19365756
On-line electrochemistry/liquid chromatography/mass spectrometry for the simulation of pesticide metabolism.	2009-01	18842426
Toxicity of six novel fungicides and sulphur to Galendromus occidentalis (Acari: Phytoseiidae).	2009-01	18792796
Baseline sensitivity of Stemphylium vesicarium, the causal agent of pear brown spot, to boscalid.	2009	20222565
Palladium-catalyzed direct arylation of nitro-substituted aromatics with aryl halides.	2008-10-16	18811176
Characterization of mutations in the iron-sulphur subunit of succinate dehydrogenase correlating with Boscalid resistance in Alternaria alternata from California pistachio.	2008-06	18944299
Diagnostic tools to identify black aspergilli.	2007	18490945
Pesticides selectivity list to beneficial arthropods in four field vegetable crops.	2007	18399430
Screening preharvest/postharvest strategies to prevent fruit rot decay.	2007	18396828
Signum, a new fungicide for control of leaf diseases in outdoor vegetables.	2005	16637178
Developing an ecotoxicological testing standard for predatory mites in Australia: acute and sublethal effects of fungicides on Euseius victoriensis and Galendromus occidentalis (Acarina: Phytoseiidae).	2004-06	15279268
Use of PRZM-3 to validate a laboratory to field degradation conceptual model.	2004-01	14727736
Signum, a new fungicide with interesting properties in resistance management of fungal diseases in strawberries.	2004	15756865

Patents

Sample Use Guides

In Vivo Use Guide

Oral: LD50 Species: rat (male/female) Value: > 2,000 mg/kg

Route of Administration: Oral

In Vitro Use Guide

Boscalid exhibited the potent antifungal effect on R. solani with an EC50 value of 1.758 mg/L.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:20:49 GMT 2025` Edited by `admin` on `Mon Mar 31 19:20:49 GMT 2025`
Record UNII	32MS8ZRD1V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EMERALD

Preferred Name

English

BOSCALID

Common Name

English

BAS 510 F

Code

English

BOSCALID [MI]

Common Name

English

BOSCALID [ISO]

Common Name

English

ENDURA

Brand Name

English

BAS-510

Common Name

English

NICOBIFEN

Common Name

English

BOSCALID [HSDB]

Common Name

English

2-CHLORO-N-(4'-CHLOROBIPHENYL-2-YL)NICOTINAMIDE

Systematic Name

English

2-CHLORO-N-(4'-CHLORO(1,1'-BIPHENYL)-2-YL)-3-PYRIDINECARBOXAMIDE

Systematic Name

English

BAS 510

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

128008