Nitrothal-isopropyl is a fungicide, used, usually in combination with other fungicides, to control fungal pathogens on a variety of crops including fruit and vegetables. Nitrothal-isopropyl is registered for use in South Africa, Australia and New Zealand but it is not registered by the USA. Nitrothal-isopropyl is protectively active against powdery mildews and used in combination with sulphur or metiram in apples. Combinations of nitrothal-isopropyl with tridemorph greatly increased the effectiveness against Erysiphe cichoracearum on melons. Nitrothal-isopropyl is a selective fungicide applied towards control of the development of many side effects of diseases caused by microorganisms in plant breeding of agricultural crops. It has been applied for the control of Podosphaera leucotricha in apple trees, Phytophthora infestans in tomato and potato, and Septoria apii in celery as well as Bremia lactucae in lettuce cultivation. Nitrothal-isopropyl is also applied as a seed treatment, in order to combat diseases of vegetable and ornamental plants. It is used in forestry for diseases causing needles drooping as well. In humans NT can cause eyes, skin, and respiration system irritation. Nitrothal-isopropyl is classified as a third-class toxicity pesticide for mammals.