U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 12591 - 12600 of 12951 results

Status:
Possibly Marketed Outside US
Source:
DECAPINOL by Ferrosan
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)



Delmopinol, a surface-active cationic agent. It was approved by FDA under the name Decapinol for the treatment of gingivitis and prevention of periodontitis. The drug interacts with the early acquired pellicle, the thin layer of saliva polymers and proteins covering teeth and gums, and forms a barrier over teeth and gums. This barrier prevents the microbial adhesion and colonisation on the tooth and gum surface. Delmopinol itself has no bactericidal activity.
Status:
Possibly Marketed Outside US
Source:
Japan:Temocapril Hydrochloride
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Temocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States but is approved in Japan and South Korea. Temocapril can also be used in hemodialysis patients without risk of serious accumulation.
Status:
Possibly Marketed Outside US
Source:
Velnacrine maleate by Hoechst-Roussel (Aventis)
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)



Velnacrine (9-amino-1,2,3,4-tetrahydroacridin-1-ol) is an inhibitor of acetylcholinesterase. It was studied for the treatment of Alzheimer's disease however development was discontinued. There has been no research into the use of velnacrine as a cognitive enhancer in the treatment of Alzheimer's disease since 1994. The FDA peripheral and CNS drug advisory board voted unanimously against recommending approval. This review shows the toxic nature of velnacrine, and provides no evidence of efficacy.
Status:
Possibly Marketed Outside US
Source:
Canada:DIBUNATE SODIUM
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Dibunate (also known as Becantex, Becantyl, Linctussal, L-1633, and described as the 2,6-isomer or the 2,7-isomer) is an antitussive oral medication that was used in many counties all over the world. The current marketing status of the drug is unknown and is supposed to be "discontinued".
Status:
Possibly Marketed Outside US
Source:
Suprefact Depot 2 Months by Sanofi Aventis [Canada]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR). Buserelin is used for palliative treatment of prostate cancer, and for treatment of endometriosis. Buserelin is also used for infertility treatment to prepare the pituitary gland before starting treatment with gonadotrophins (FSH and LH) to artificially stimulate ovulation.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

CHLORAL HYDRATE ANTIPYRINE is a 1:1 mixture of antipyrine with chloral hydrate. It was used as a hypnotic drug known as HYPNAL in the late 19th century.
Cibenzoline is a class I sodium channel blocker antiarrhythmic drug available in a limited number of countries. Cibenzoline also has moderate calcium channel blocking (class IV) effects and prolongs the action potential duration through its potassium channel blocking (class III) effect. It is used for the treatment of supraventricular and ventricular arrhythmias, and in obstructive hypertrophic cardiomyopathy.
Status:
Possibly Marketed Outside US
Source:
Japan:Bevonium Methylsulfate
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Bevonium is a parasympatolytic antimuscarinic compound. It possesses spasmolytic properties. The use of the drug is discontinued.
Status:
Possibly Marketed Outside US
Source:
Canada:POTASSIUM OXALATE
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Potassium Trihydrogen Dioxalate is a Potassium salt used in photography, marble grinding, and in metal polishing. Potassium Trihydrogen Dioxalate is strongly irritating to eyes, mucous and gastrointestinal tract. Potassium Trihydrogen Dioxalate may cause cardiac failure and death after oral administration
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Dihexyverine (Metaspas, Spasmodex) is an anticholinergic and direct smooth muscle relaxant (spasmolytic). Dihexyverine is sold in France under the brand name Spasmodex. It is indicated for the treatment of the gastrointestinal tract disorders. Dihexyverine is a muscarinic acetylcholine receptor antagonist.

Showing 12591 - 12600 of 12951 results