TOLPROPAMINE HYDROCHLORIDE

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NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H23N.ClH
Molecular Weight	289.843
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TOLPROPAMINE HYDROCHLORIDE

Structure Search

SMILES

Cl.CN(C)CCC(C1=CC=CC=C1)C2=CC=C(C)C=C2

InChI

InChIKey=NKTYRULGQCXXSI-UHFFFAOYSA-N

InChI=1S/C18H23N.ClH/c1-15-9-11-17(12-10-15)18(13-14-19(2)3)16-7-5-4-6-8-16;/h4-12,18H,13-14H2,1-3H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C18H23N
Molecular Weight	253.3819
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: http://www.hmdb.ca/metabolites/HMDB0240238 | https://www.drugfuture.com/chemdata/tolpropamine.html

TOLPROPAMINE is an alkylamine H1-antihistamine used as an antipruritic and topical antihistaminic.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Antimycobacterial antihistaminics].	1989 Aug	2513793
Chemistry of dicationic electrophiles: superacid-catalyzed reactions of amino acetals.	2002 Jul 12	12098332

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:36:37 GMT 2023` Edited by `admin` on `Fri Dec 15 18:36:37 GMT 2023`
Record UNII	1P6C450YET
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TOLPROPAMINE HYDROCHLORIDE

Common Name

English

Tolpropamine hydrochloride [WHO-DD]

Common Name

English

TOLPROPAMINE HYDROCHLORIDE [MART.]

Common Name

English

TOLPROPAMINE HCL

Common Name

English

BENZENEPROPANAMINE, N,N,4-TRIMETHYL-.GAMMA.-PHENYL-, HYDROCHLORIDE (1:1)

Systematic Name

English

N,N-DIMETHYL-3-PHENYL-3-P-TOLYLPROPYLAMINE HYDROCHLORIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

Code System Code Type Description

MESH

C005547

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

PRIMARY

CAS

3339-11-5

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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SMS_ID

100000084657

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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NCI_THESAURUS

C97705

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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EPA CompTox

DTXSID40955005

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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FDA UNII

1P6C450YET

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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ECHA (EC/EINECS)

222-082-9

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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EVMPD

SUB04913MIG

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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PUBCHEM

102987

Created by admin on Fri Dec 15 18:36:37 GMT 2023 , Edited by admin on Fri Dec 15 18:36:37 GMT 2023

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