U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 811 - 820 of 2596 results

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

There has been little to no interest in the pharmacological application of the glutamate cobalt complex, but there are some published results investigating the role of glutamate-induced cobalt uptake in taste cells which occurs mainly via kainate type non-N-methyl-D-aspartate glutamate receptors (GluRs).
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

6,7-dimethoxyquinazoline-2,4(1H,3H)-dione is useful as a building block in the synthesis of alpha adrenergic receptor antagonists such as Prazosin, Bunazosin and Doxazosin, and which are useful as antihypertensive agents.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Meso form of cystine (cystine, meso) reacts three times faster than L-cystine.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Epiquinidine is an alkaloid derived from the bark of the cinchona tree. The most abundant constituents of the Cinchona barks are two pairs of erythro diastereoisomers: quinineand quinidine, which are active antimalarials. Their threo epimers, epiquinine and epiquinidine, are practically inactive. Compared to quinine and quinidine, the 9-epimers had significantly reduced hemozoin inhibition efficiency and did not affect pH-dependent aggregation of ferriprotoporphyrin IX (FPIX) heme. Magnetic susceptibility measurements showed that the 9-epimers perturb FPIX monomer-dimer equilibrium in favor of monomer, and UV-visible (VIS) titrations showed that Epiquinine and Epiquinidine bind monomer with similar affinity relative to quinine and quinidine. However, unique ring proton shifts in the presence of zinc(II) protoporphyrin IX (ZnPIX) indicate that binding of the 9-epimers to monomeric heme is via a distinct geometry.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

POTASSIUM O-XYLENE-4-SULFONATE is a surfactant agent.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Potassium PCA is a potassium salt of L-Pyrrolidone carboxylic acid, moisturiser. Controls osmotic balance of skin cells. Used in skin care. Potassium PCA is sold under the names Kalidone® and Aquaregul-K by the company UCIB (Solabia).
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Potassium Butylparaben is an approved preservative for cosmetics.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

N-Acetyl dihydrosphingosine is dihydroceramide derivative and isomer of cedefingol with minimal anticancer activity. N-Acetyl dihydrosphingosine shows minimal apoptotic activity against human leukemia cells.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

The information related to the biological and/or pharmacological activity of palmitoyl alanine is absent.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

PINANEDIOL, (+)- is a precursor to a chiral allyl boronate used in a preparation of chiral β-hydroxyallylsilanes.