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Details

Stereochemistry ABSOLUTE
Molecular Formula C5H6NO3.K
Molecular Weight 167.2043
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of POTASSIUM PIDOLATE

SMILES

[K+].[O-]C(=O)[C@@H]1CCC(=O)N1

InChI

InChIKey=WKHCFXKQKDNLEB-DFWYDOINSA-M
InChI=1S/C5H7NO3.K/c7-4-2-1-3(6-4)5(8)9;/h3H,1-2H2,(H,6,7)(H,8,9);/q;+1/p-1/t3-;/m0./s1

HIDE SMILES / InChI

Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H6NO3
Molecular Weight 128.106
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Potassium PCA is a potassium salt of L-Pyrrolidone carboxylic acid, moisturiser. Controls osmotic balance of skin cells. Used in skin care. Potassium PCA is sold under the names Kalidone® and Aquaregul-K by the company UCIB (Solabia).

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
The metabolism of L-pyroglutamic acid in fibroblasts from a patient with pyroglutamic aciduria: the demonstration of an L-pyroglutamate hydrolase system.
1972 May
Patents

Sample Use Guides

Skin cleansing - 0.085%; Body and hand products not spray - 0.05% Moisturizing products not spray - 0.005%
Route of Administration: Topical
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:04:55 GMT 2025
Edited
by admin
on Mon Mar 31 21:04:55 GMT 2025
Record UNII
H004M3556Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
POTASSIUM PCA
INCI  
INCI  
Preferred Name English
POTASSIUM PIDOLATE
Common Name English
L-PROLINE, 5-OXO-, MONOPOTASSIUM SALT
Common Name English
(S)-PYRROLIDONE-5-CARBOXYLIC ACID POTASSIUM SALT
Common Name English
POTASSIUM 5-OXO-L-PROLINATE
Systematic Name English
POTASSIUM L-PYROGLUTAMATE
Common Name English
L-PROLINE, 5-OXO-, POTASSIUM SALT (1:1)
Common Name English
KALIDONE
Brand Name English
Potassium pidolate [WHO-DD]
Common Name English
POTASSIUM (S)-2-PYRROLIDONE-5-CARBOXYLATE
Systematic Name English
PROLINE, 5-OXO-, POTASSIUM SALT, L-
Common Name English
Code System Code Type Description
CAS
4810-50-8
Created by admin on Mon Mar 31 21:04:55 GMT 2025 , Edited by admin on Mon Mar 31 21:04:55 GMT 2025
PRIMARY
ECHA (EC/EINECS)
225-373-9
Created by admin on Mon Mar 31 21:04:55 GMT 2025 , Edited by admin on Mon Mar 31 21:04:55 GMT 2025
PRIMARY
FDA UNII
H004M3556Q
Created by admin on Mon Mar 31 21:04:55 GMT 2025 , Edited by admin on Mon Mar 31 21:04:55 GMT 2025
PRIMARY
PUBCHEM
23684897
Created by admin on Mon Mar 31 21:04:55 GMT 2025 , Edited by admin on Mon Mar 31 21:04:55 GMT 2025
PRIMARY
EPA CompTox
DTXSID40197423
Created by admin on Mon Mar 31 21:04:55 GMT 2025 , Edited by admin on Mon Mar 31 21:04:55 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE