(S)-Aminoglutethimide is S-isomer of racemate anti-steroid drug Aminoglutethimide, marketed by Novartis for the treatment of Cushing syndrome and other conditions. (S)-Aminoglutethimide was shown to less active than (R)-isomer in inhibiting corticosteroid release in rats, less potent in inhibiting aromatization of testosterone by human placental microsomes.

1,1-Diethoxyethane or acetal is flavoring and cosmetic fragrance agent. In perfumery, it’s used in head notes to add freshness to hyacinth, ivy and marine composition. It has been reported in sake, whisky and rum. It presents in list of “Everything added food in the United States (EAFUS)”. LD50 orally in rats: 4.57 g/kg.

Methyl 3,4,5-trimethoxybenzoate is a derivative of gallic acid.

Zinc Oxalate is a derivative of Oxalic Acid. Zinc Oxalate is freely soluble in water. Zinc Oxalate is a White crystalline powder. Zinc oxalate, thermally decomposed, is used to obtain zinc oxide, which is a sunscreen ingredient. Zinc Oxalate is used in metal treatment industry & in pharmaceutical applications. Anti-caking agents such as zinc oxalates have antiseptic properties and the ability to kill bacteria.

Dibenzosuberone is used for the organic synthesis. Dibenzosuberone derivatives are potent inhibitors of p38 mitogen-activated protein kinase. They may foster a new generation of anti-inflammatory drugs. Dibenzosuberone derivatives are potential tricyclic antidepressants and anti-tumor agents.

Domoic acid is one of the best-known marine toxins, causative of important neurotoxic alterations. In the year 1987, domoic acid was responsible for four deaths and the illness of more than 100 people after consuming blue mussels (Mytilus edulis) harvested in the Cardigan Bay of Prince Edward Island, Canada. The symptomatology comprised three kinds of signs: gastrointestinal (nausea, vomiting,), cardiovascular (unstable blood pressure and arrhythmias), and neurological signs (disorientation, confusion, hallucinations, coma, and memory impairment). After this event was discovered the domoic acid epileptic. Nearly a year after the amnesic shellfish poisoning event, an 84 years old male survivor re-experienced severe seizures and was diagnosed with temporal lobe epilepsy caused by domoic acid intoxication. This toxin has a high affinity for the glutamate receptors (GluRs) subtypes: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and KA receptors. The binding of domoic acid to receptors provokes an increase of calcium (Ca2+) levels, causing the release of Glu to the extracellular space, and the activation of N-methyl-d-aspartate (NMDA) receptors. The histological consequences of these cellular alterations comprise astrocytosis, cytoskeletal disarrangement and, finally, cell death.

NGD 94-1 is high affinity D4 receptor ligand, shows selective over D1, D2, D3 and D5 receptors. Displays antagonist activity at the human D4.2 receptor (Ki = 3.6 nM in transfected CHO cells) and exhibits agonist activity at the D4.4 receptor in HEK 293 cells.

α-Hexachlorcyclohexane a byproduct of a production of insecticide lindane (γ-hexachlorocyclohexane). α-Hexachlorcyclohexane is a major (60-70%) component of technical grade hexachlorocyclohexane. It is a widespread environment pollutant and cause liver tumors in rats and mice.

Fluticasone Acetate is an impurity in commercial preparations of Fluticasone propionate, a derivative of Flumethasone.

(1,2,6,7-3H)-Testosterone is a radiolabeled form of the corresponding steroid hormone. It can be used to study testosterone metabolism and androgen receptor binding in tissues.