DIBENZOSUBERONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H12O
Molecular Weight	208.2552
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=BMVWCPGVLSILMU-UHFFFAOYSA-N

InChI=1S/C15H12O/c16-15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-8H,9-10H2

HIDE SMILES / InChI

Molecular Formula	C15H12O
Molecular Weight	208.2552
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/22676210 | https://www.ncbi.nlm.nih.gov/pubmed/18007539 | https://www.google.com/patents/EP2152258A1

Dibenzosuberone is used for the organic synthesis. Dibenzosuberone derivatives are potent inhibitors of p38 mitogen-activated protein kinase. They may foster a new generation of anti-inflammatory drugs. Dibenzosuberone derivatives are potential tricyclic antidepressants and anti-tumor agents.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Synthesis of novel, potentially biologically active dibenzosuberone derivatives.	2005 Dec 31	18007539
2H NMR and X-ray diffraction studies of methyl rotation in crystals of ortho-methyldibenzocycloalkanones.	2005 Jul	16026685
Sensitive extractive spectrophotometric methods for the determination of nortriptyline hydrochloride in pharmaceutical formulations.	2007 Dec	18057736
Dibenzosuberones as p38 mitogen-activated protein kinase inhibitors with low ATP competitiveness and outstanding whole blood activity.	2013 Jan 10	23270382

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:46:00 UTC 2023` Edited by `admin` on `Fri Dec 15 15:46:00 UTC 2023`
Record UNII	8ETK71TH0H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIBENZOSUBERONE

Common Name

English

NORTRIPTYLINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

DIBENZOCYCLOHEPTENONE

Systematic Name

English

10,11-DIHYDRO-5H-DIBENZO(A,D)(7)ANNULEN-5-ONE

Common Name

English

5H-DIBENZO(A,D)CYCLOHEPTEN-5-ONE, 10,11-DIHYDRO-

Systematic Name

English

AMITRIPTYLINE RELATED COMPOUND A

Common Name

English

2,3:6,7-DIBENZOSUBERONE

Common Name

English

10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTAN-5-ONE

Common Name

English

NSC-49727

Code

English

AMITRIPTYLINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

AMITRIPTYLINE RELATED COMPOUND A [USP-RS]

Common Name

English

DIBENZO(A,D)CYCLOHEPTA(1,4)DIEN-5-ONE

Common Name

English

DIBENZOSUBERAN-5-ONE

Common Name

English

10,11-DIHYDRODIBENZO(A,D)CYCLOHEPTEN-5-ONE

Systematic Name

English

DIBENZO(A,D)CYCLOHEPTADIEN-5-ONE

Common Name

English

Code System Code Type Description

PUBCHEM

14589