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Details

Stereochemistry ACHIRAL
Molecular Formula C15H12O
Molecular Weight 208.2552
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIBENZOSUBERONE

SMILES

O=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=BMVWCPGVLSILMU-UHFFFAOYSA-N
InChI=1S/C15H12O/c16-15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-8H,9-10H2

HIDE SMILES / InChI
Molecular Formula C15H12O
Molecular Weight 208.2552
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Dibenzosuberone is used for the organic synthesis. Dibenzosuberone derivatives are potent inhibitors of p38 mitogen-activated protein kinase. They may foster a new generation of anti-inflammatory drugs. Dibenzosuberone derivatives are potential tricyclic antidepressants and anti-tumor agents.

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Synthesis of novel, potentially biologically active dibenzosuberone derivatives.
2005 Dec 31
Patents

Patents

05595989
1
DE1810705
2
EP2152258 A1
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:46:00 GMT 2023
Edited
by admin
on Fri Dec 15 15:46:00 GMT 2023
Record UNII
8ETK71TH0H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIBENZOSUBERONE
Common Name English
NORTRIPTYLINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
Common Name English
DIBENZOCYCLOHEPTENONE
Systematic Name English
10,11-DIHYDRO-5H-DIBENZO(A,D)(7)ANNULEN-5-ONE
Common Name English
5H-DIBENZO(A,D)CYCLOHEPTEN-5-ONE, 10,11-DIHYDRO-
Systematic Name English
AMITRIPTYLINE RELATED COMPOUND A
USP-RS  
Common Name English
2,3:6,7-DIBENZOSUBERONE
Common Name English
10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTAN-5-ONE
Common Name English
NSC-49727
Code English
AMITRIPTYLINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
Common Name English
AMITRIPTYLINE RELATED COMPOUND A [USP-RS]
Common Name English
DIBENZO(A,D)CYCLOHEPTA(1,4)DIEN-5-ONE
Common Name English
DIBENZOSUBERAN-5-ONE
Common Name English
10,11-DIHYDRODIBENZO(A,D)CYCLOHEPTEN-5-ONE
Systematic Name English
DIBENZO(A,D)CYCLOHEPTADIEN-5-ONE
Common Name English
Code System Code Type Description
PUBCHEM
14589
Created by admin on Fri Dec 15 15:46:00 GMT 2023 , Edited by admin on Fri Dec 15 15:46:00 GMT 2023
PRIMARY
CAS
1210-35-1
Created by admin on Fri Dec 15 15:46:00 GMT 2023 , Edited by admin on Fri Dec 15 15:46:00 GMT 2023
PRIMARY
RS_ITEM_NUM
1029013
Created by admin on Fri Dec 15 15:46:00 GMT 2023 , Edited by admin on Fri Dec 15 15:46:00 GMT 2023
PRIMARY
EPA CompTox
DTXSID4049400
Created by admin on Fri Dec 15 15:46:00 GMT 2023 , Edited by admin on Fri Dec 15 15:46:00 GMT 2023
PRIMARY
ECHA (EC/EINECS)
214-912-3
Created by admin on Fri Dec 15 15:46:00 GMT 2023 , Edited by admin on Fri Dec 15 15:46:00 GMT 2023
PRIMARY
FDA UNII
8ETK71TH0H
Created by admin on Fri Dec 15 15:46:00 GMT 2023 , Edited by admin on Fri Dec 15 15:46:00 GMT 2023
PRIMARY
NSC
49727
Created by admin on Fri Dec 15 15:46:00 GMT 2023 , Edited by admin on Fri Dec 15 15:46:00 GMT 2023
PRIMARY
Related Record Type Details
Structure of AMITRIPTYLINE HYDROCHLORIDE
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CHROMATOGRAPHIC PURITY (HPLC/UV)
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Structure of CYPROHEPTADINE HYDROCHLORIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of NORTRIPTYLINE HYDROCHLORIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of AMITRIPTYLINE HYDROCHLORIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
NIH
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