U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Showing 1 - 10 of 12 results

Status:
US Approved Rx (2021)
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)



Pyrimethamine, sold under the trade name Daraprim, is one of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. In addition it was approved in Chemoprophylaxis of Malaria. However, resistance to p...
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Azaerythromycin A is a novel intermediate of Azithromycin which acts as an antibiotic. Azithromycin binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.
Norharman or beta-carboline (9H-pyrido[3,4-b]indole) is a neuroactive alkaloid first isolated from Peganum harmala L. It is implicated in a number of human diseases including Parkinson's disease, tremor, addiction and cancer. Norharman formed endogen...
Status:
US Previously Marketed
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Vanillin (4-hydroxy-3-methoxybenzaldehyde), a pleasant smelling organic aromatic compound, is widely used as a flavoring additive in food, beverage, cosmetic and drug industries. It is reported to cross the blood brain barrier and also displayed anti...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Arprinocid is a coccidiostat used in veterinary medicine. Effective against coccidiosis in poultry.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Sulfachloropyrazine, a sulfonamide, was developed as a drug for poultry coccidiosis. Sulfachloropyrazine was found to be a therapeutic option for T. gondii infection in animals.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Spiramycins are macrolides produced by cultures of Streptomyces ambofaciens from the soil of northern France. The mixture of spiramycins have been successfully separated into three different components termed as Spiramycin I, II and III, which differ...
Status:
US Approved Rx (2021)
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)



Pyrimethamine, sold under the trade name Daraprim, is one of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. In addition it was approved in Chemoprophylaxis of Malaria. However, resistance to p...
Status:
US Approved Rx (2021)
First approved in 1953

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pyrimethamine, sold under the trade name Daraprim, is one of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. In addition it was approved in Chemoprophylaxis of Malaria. However, resistance to p...
Status:
US Approved Rx (2021)
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)



Pyrimethamine, sold under the trade name Daraprim, is one of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. In addition it was approved in Chemoprophylaxis of Malaria. However, resistance to p...

Showing 1 - 10 of 12 results