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Details

Stereochemistry ACHIRAL
Molecular Formula C12H9ClFN5
Molecular Weight 277.685
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ARPRINOCID

SMILES

NC1=NC=NC2=C1N=CN2CC3=C(F)C=CC=C3Cl

InChI

InChIKey=NAPNOSFRRMHNBJ-UHFFFAOYSA-N
InChI=1S/C12H9ClFN5/c13-8-2-1-3-9(14)7(8)4-19-6-18-10-11(15)16-5-17-12(10)19/h1-3,5-6H,4H2,(H2,15,16,17)

HIDE SMILES / InChI

Description

Arprinocid is a coccidiostat used in veterinary medicine. Effective against coccidiosis in poultry.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
7.0 µM [IC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Unknown
Curative
ARPOCOX

PubMed

Sample Use Guides

In Vivo Use Guide
Chicks: Medication of chicks with 70 p.p.m. arprinocid in the food, starting 2 days prior to inoculation with Eimeria tenella, resulted in decreased oocyst production and oocyst sporulation.
Route of Administration: Oral
In Vitro Use Guide
Arprinocid inhibited growth of Toxoplasma gondii in human fibroblasts at 2 ug/ml.