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Details

Stereochemistry RACEMIC
Molecular Formula C25H29N3O3
Molecular Weight 419.5161
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ADIMOLOL

SMILES

CC(C)(CCN1C(=O)NC2=C1C=CC=C2)NCC(O)COC3=CC=CC4=C3C=CC=C4

InChI

InChIKey=YWRIUGFSIQMHJK-UHFFFAOYSA-N
InChI=1S/C25H29N3O3/c1-25(2,14-15-28-22-12-6-5-11-21(22)27-24(28)30)26-16-19(29)17-31-23-13-7-9-18-8-3-4-10-20(18)23/h3-13,19,26,29H,14-17H2,1-2H3,(H,27,30)

HIDE SMILES / InChI

Molecular Formula C25H29N3O3
Molecular Weight 419.5161
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Adimolol is an antihypertensive agent with a potent antagonist of central beta-adrenoceptors and has a weaker alpha 1-adrenolytic action. The central alpha 2-antagonistic effect is either very weak or absent. The reduction in beta-adrenoceptor number following adimolol suggests that this prolonged effect may not be solely due to competitive antagonism but may additionally depend upon non-competitive antagonism at beta-adrenoceptors. Adimolol reduced supine, standing and exercise heart rates in a dose dependent manner.

Approval Year

Sample Use Guides

In Vivo Use Guide
Single dose - 25, 200, 400 or 800 mg
Route of Administration: Oral
Substance Class Chemical
Record UNII
B6CJY5K2ST
Record Status Validated (UNII)
Record Version