Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C25H29N3O3.ClH |
| Molecular Weight | 455.977 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(C)(CCN1C(=O)NC2=CC=CC=C12)NCC(O)COC3=CC=CC4=CC=CC=C34
InChI
InChIKey=WXUATBZTSZGPQT-UHFFFAOYSA-N
InChI=1S/C25H29N3O3.ClH/c1-25(2,14-15-28-22-12-6-5-11-21(22)27-24(28)30)26-16-19(29)17-31-23-13-7-9-18-8-3-4-10-20(18)23;/h3-13,19,26,29H,14-17H2,1-2H3,(H,27,30);1H
| Molecular Formula | C25H29N3O3 |
| Molecular Weight | 419.5161 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Adimolol is an antihypertensive agent with a potent antagonist of central beta-adrenoceptors and has a weaker alpha 1-adrenolytic action. The central alpha 2-antagonistic effect is either very weak or absent. The reduction in beta-adrenoceptor number following adimolol suggests that this prolonged effect may not be solely due to competitive antagonism but may additionally depend upon non-competitive antagonism at beta-adrenoceptors. Adimolol reduced supine, standing and exercise heart rates in a dose dependent manner.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:16:51 UTC 2023
by
admin
on
Sat Dec 16 14:16:51 UTC 2023
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| Record UNII |
D9QT537UWA
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID00997123
Created by
admin on Sat Dec 16 14:16:51 UTC 2023 , Edited by admin on Sat Dec 16 14:16:51 UTC 2023
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75708-29-1
Created by
admin on Sat Dec 16 14:16:51 UTC 2023 , Edited by admin on Sat Dec 16 14:16:51 UTC 2023
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D9QT537UWA
Created by
admin on Sat Dec 16 14:16:51 UTC 2023 , Edited by admin on Sat Dec 16 14:16:51 UTC 2023
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10049692
Created by
admin on Sat Dec 16 14:16:51 UTC 2023 , Edited by admin on Sat Dec 16 14:16:51 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
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SOLVATE->ANHYDROUS | |||
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |