U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
127998
Substance Class Protein
Created
by admin
on Sun Dec 18 09:17:05 UTC 2022
Edited
by admin
on Sun Dec 18 09:17:05 UTC 2022
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
3T7136LE8K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALPHA-1A ADRENERGIC RECEPTOR
Common Name English
ADRA1C
Common Name English
ALPHA-1A ADRENOCEPTOR
Common Name English
ALPHA-1A ADRENORECEPTOR
Common Name English
Code System Code Type Description
FDA UNII
3T7136LE8K
Created by admin on Sun Dec 18 09:17:08 UTC 2022 , Edited by admin on Sun Dec 18 09:17:08 UTC 2022
PRIMARY
PHAROS
P35348
Created by admin on Sun Dec 18 09:17:08 UTC 2022 , Edited by admin on Sun Dec 18 09:17:08 UTC 2022
PRIMARY
UNIPROT
P35348
Created by admin on Sun Dec 18 09:17:08 UTC 2022 , Edited by admin on Sun Dec 18 09:17:08 UTC 2022
PRIMARY
WIKIPEDIA
ALPHA-1_ADRENERGIC_RECEPTOR
Created by admin on Sun Dec 18 09:17:08 UTC 2022 , Edited by admin on Sun Dec 18 09:17:08 UTC 2022
PRIMARY
From To
1_99 1_176
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_7
N 1_13
N 1_22
Related Record Type Details
Structure of LABETALOL
AGONIST -> TARGET
Structure of NAFTOPIDIL
INHIBITOR -> TARGET
Ki
Structure of RS-97078 FREE BASE
INHIBITOR -> TARGET
Structure of BENZPHETAMINE
AGONIST -> TARGET
Structure of SILODOSIN
INHIBITOR -> TARGET
Selectivity of silodosin determined in cloned human ?1-adrenergic receptor (?1-AR) subtypes in cultured Chinese hamster ovary cells.Silodosin has greater affinity for the ?1A-adrenergic receptor than for the ?1B-adrenergic receptor (by a factor of 583), minimizing the propensity for blood pressure-related adverse effects mediated by ?1B blockade.
Ki
Structure of XYLOMETAZOLINE
AGONIST -> TARGET
Structure of PSEUDOEPHEDRINE
AGONIST -> TARGET
Structure of TERAZOSIN
INHIBITOR -> TARGET
Structure of OXEDRINE
AGONIST -> TARGET
Structure of DROXIDOPA
AGONIST -> TARGET
Structure of MOXISYLYTE
AGONIST -> TARGET
Structure of APRACLONIDINE
AGONIST -> TARGET
Structure of AROTINOLOL
AGONIST -> TARGET
Structure of MIDODRINE
AGONIST -> TARGET
Structure of PHENTOLAMINE
AGONIST -> TARGET
Structure of RS-100975
INHIBITOR -> TARGET
Structure of CHLORPROMAZINE
INHIBITOR -> TARGET
Structure of LABETALOL
INHIBITOR -> TARGET
Ki
Structure of NIAPRAZINE
INHIBITOR -> TARGET
Ki
Structure of ETILEFRINE
AGONIST -> TARGET
Structure of PRAZOSIN
INHIBITOR -> TARGET
Structure of 6-FLUORO-DMT
AGONIST -> TARGET
Structure of OXYMETHOLONE
AGONIST -> TARGET
Structure of PALIPERIDONE
INHIBITOR -> TARGET
INHIBITOR
Ki
Structure of TETRAHYDROZOLINE
AGONIST -> TARGET
Structure of PHENYLEPHRINE
AGONIST -> TARGET
Structure of RWJ-38063
INHIBITOR -> TARGET
Structure of CIRAZOLINE
AGONIST -> TARGET
Structure of INDORAMIN
AGONIST -> TARGET
Structure of NAPHAZOLINE
AGONIST -> TARGET
Structure of TOLAZOLINE
AGONIST -> TARGET
Structure of TIAMENIDINE
AGONIST -> TARGET
Structure of 4-MA
AGONIST -> TARGET
Structure of EPINEPHRINE
AGONIST -> TARGET
Structure of ROLUPERIDONE
INHIBITOR -> TARGET
Structure of ADIMOLOL
INHIBITOR -> TARGET
Structure of ALFUZOSIN
INHIBITOR -> TARGET
Structure of METHOXAMINE
AGONIST -> TARGET
Structure of DAPIPRAZOLE
INHIBITOR -> TARGET
Structure of SHI-437 FREE BASE
INHIBITOR -> TARGET
Structure of NOREPINEPHRINE
AGONIST -> TARGET
Structure of PHENDIMETRAZINE
AGONIST -> TARGET
Structure of TRIMAZOSIN
AGONIST -> TARGET
Structure of TRIFLUOPERAZINE
INHIBITOR -> TARGET
Structure of OXYMETAZOLINE
AGONIST -> TARGET
Structure of CUMI-101 C-11
RADIOLIGAND->TARGET
REPRESENTIVE ALPHA-1 ADRENERGIC RECEPTOR
Ki
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966