Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.2304 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@@H](COC(N)=O)CC1=CC=CC=C1
InChI
InChIKey=UCTRAOBQFUDCSR-SECBINFHSA-N
InChI=1S/C10H14N2O2/c11-9(7-14-10(12)13)6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H2,12,13)/t9-/m1/s1
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.2304 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Oct 21 22:40:18 UTC 2019
by
admin
on
Mon Oct 21 22:40:18 UTC 2019
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| Record UNII |
939U7C91AI
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C78272
Created by
admin on Mon Oct 21 22:40:18 UTC 2019 , Edited by admin on Mon Oct 21 22:40:18 UTC 2019
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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10117
Created by
admin on Mon Oct 21 22:40:18 UTC 2019 , Edited by admin on Mon Oct 21 22:40:18 UTC 2019
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PRIMARY | |||
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178429-62-4
Created by
admin on Mon Oct 21 22:40:18 UTC 2019 , Edited by admin on Mon Oct 21 22:40:18 UTC 2019
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PRIMARY | |||
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10130337
Created by
admin on Mon Oct 21 22:40:18 UTC 2019 , Edited by admin on Mon Oct 21 22:40:18 UTC 2019
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PRIMARY | |||
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C152389
Created by
admin on Mon Oct 21 22:40:18 UTC 2019 , Edited by admin on Mon Oct 21 22:40:18 UTC 2019
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT | |||
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TRANSPORTER -> INHIBITOR |
WEAK
IC50
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TRANSPORTER -> INHIBITOR |
WEAK
IC50
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BINDER->LIGAND |
BINDING
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EXCRETED UNCHANGED |
Approximately 95% of the dose was recovered in urine as unchanged solriamfetol, 1% or less of the administered dose was recovered in urine as the minor inactive metabolite N-acetyl solriamfetol.
URINE
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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METABOLITE INACTIVE -> PARENT | |||
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METABOLITE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Volume of Distribution | PHARMACOKINETIC |
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| Biological Half-life | PHARMACOKINETIC |
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| ORAL BIOAVAILABILITY | PHARMACOKINETIC |
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| Tmax | PHARMACOKINETIC |
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