Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C24H27N5O2 |
| Molecular Weight | 417.5035 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CCN(CC1)C2=CC3=C(C=C2)N=CN(C3=O)C4=C(C)C=CC(=C4)C(=O)NC5CC5
InChI
InChIKey=ZMAZXHICVRYLQN-UHFFFAOYSA-N
InChI=1S/C24H27N5O2/c1-16-3-4-17(23(30)26-18-5-6-18)13-22(16)29-15-25-21-8-7-19(14-20(21)24(29)31)28-11-9-27(2)10-12-28/h3-4,7-8,13-15,18H,5-6,9-12H2,1-2H3,(H,26,30)
| Molecular Formula | C24H27N5O2 |
| Molecular Weight | 417.5035 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The p38 MAP kinase pathway as a therapeutic target in inflammatory disease. | 2004 Aug |
|
| Potential of p38-MAPK inhibitors in the treatment of ischaemic heart disease. | 2007 Nov |
|
| The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases. | 2012 Jun 15 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:01:32 UTC 2023
by
admin
on
Sat Dec 16 10:01:32 UTC 2023
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| Record UNII |
8QS8G2Y8E0
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| Record Status |
Validated (UNII)
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| Record Version |
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8QS8G2Y8E0
Created by
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11373432
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851845-37-9
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CHEMBL2031465
Created by
admin on Sat Dec 16 10:01:32 UTC 2023 , Edited by admin on Sat Dec 16 10:01:32 UTC 2023
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| Related Record | Type | Details | ||
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TARGET -> INHIBITOR |
