AZD-6703

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H27N5O2
Molecular Weight	417.5035
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCN(CC1)C2=CC=C3N=CN(C(=O)C3=C2)C4=CC(=CC=C4C)C(=O)NC5CC5

InChI

InChIKey=ZMAZXHICVRYLQN-UHFFFAOYSA-N

InChI=1S/C24H27N5O2/c1-16-3-4-17(23(30)26-18-5-6-18)13-22(16)29-15-25-21-8-7-19(14-20(21)24(29)31)28-11-9-27(2)10-12-28/h3-4,7-8,13-15,18H,5-6,9-12H2,1-2H3,(H,26,30)

HIDE SMILES / InChI

Molecular Formula	C24H27N5O2
Molecular Weight	417.5035
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases.	2012-06-15	22608965
Potential of p38-MAPK inhibitors in the treatment of ischaemic heart disease.	2007-11	17765316
The p38 MAP kinase pathway as a therapeutic target in inflammatory disease.	2004-08	15251131

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:58:38 GMT 2025` Edited by `admin` on `Mon Mar 31 22:58:38 GMT 2025`
Record UNII	8QS8G2Y8E0
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AZ-12012199

Preferred Name

English

AZD-6703

Code

English

AZD 6703 [WHO-DD]

Common Name

English

AZD6703

Common Name

English

N-CYCLOPROPYL-4-METHYL-3-(6-(4-METHYL-1-PIPERAZINYL)-4-OXO-3(4H)-QUINAZOLINYL)BENZAMIDE

Systematic Name

English

AZ12012199

Code

English

BENZAMIDE, N-CYCLOPROPYL-4-METHYL-3-(6-(4-METHYL-1-PIPERAZINYL)-4-OXO-3(4H)-QUINAZOLINYL)-

Systematic Name

English

Code System Code Type Description

FDA UNII

8QS8G2Y8E0