FURAMIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H16N4O
Molecular Weight	304.3465
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

c1cc(ccc1-c2ccc(-c3ccc(cc3)C(=N)N)o2)C(=N)N

InChI

InChIKey=ZJHZBDRZEZEDGB-UHFFFAOYSA-N

InChI=1S/C18H16N4O/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22/h1-10H,(H3,19,20)(H3,21,22)

HIDE SMILES / InChI

Molecular Formula	C18H16N4O
Molecular Weight	304.3465
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Protein-arginine N-methyltransferase 1 4 Target ID: CHEMBL5524 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24564570	Inhibitor 7701		9.40000000000000036 µM [IC50]
Quinone reductase 2 7 Target ID: CHEMBL3959 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26854376	Inhibitor 7701		35 nM [IC50]

Substance Class	Chemical Created by `admin` on `Fri Jun 25 22:48:14 UTC 2021` Edited by `admin` on `Fri Jun 25 22:48:14 UTC 2021`
Record UNII	08GH1YF0RA
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FURAMIDINE

Systematic Name

English

NSC-305831

Code

English

2,5-BIS(4-AMIDINOPHENYL)FURAN

Common Name

English

DB75

Code

English

4,4'-(2,5-FURANDIYL)BIS [BENZENECARBOXIMIDAMIDE]

Systematic Name

English

BENZENECARBOXIMIDAMIDE, 4,4'-(2,5-FURANDIYL)BIS-

Systematic Name

English

DB-75

Code

English

Code System Code Type Description

CAS

73819-26-8

Created by admin on Fri Jun 25 22:48:14 UTC 2021 , Edited by admin on Fri Jun 25 22:48:14 UTC 2021

PRIMARY

FDA UNII

08GH1YF0RA

Created by admin on Fri Jun 25 22:48:14 UTC 2021 , Edited by admin on Fri Jun 25 22:48:14 UTC 2021

PRIMARY

EPA CompTox

73819-26-8

Created by admin on Fri Jun 25 22:48:14 UTC 2021 , Edited by admin on Fri Jun 25 22:48:14 UTC 2021

PRIMARY

PUBCHEM

126437

Created by admin on Fri Jun 25 22:48:14 UTC 2021 , Edited by admin on Fri Jun 25 22:48:14 UTC 2021

PRIMARY

Related Record Type Details


					ONY583280Z

OCT-1

TRANSPORTER -> INHIBITOR


					482M00274D

OCT-2

TRANSPORTER -> INHIBITOR


					4007E25Z4Z

OCT-3

TRANSPORTER -> INHIBITOR

Related Record Type Details


					H1VG379J2X

PAFURAMIDINE

PRODRUG -> METABOLITE ACTIVE