Search results for "ORPHAN DRUG|Designated|Treatment of Huntington's Disease" in comments (approximate match)
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Cannabidiol is the major nonpsychoactive ingredient in cannabis. Cannabidiol demonstrates a range of effects that may be therapeutically useful, including anti-seizure, antioxidant, neuroprotective, anti-inflammatory, analgesic, anti-tumor, anti-psy...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
(+)-alpha-Dihydrotetrabenazine (HTBZ) is an active component of tetrabenazine. Tetrabenazine is a mixture of closely-related compounds (isomers) and is readily metabolized in the human body to HTBZ and related isomers. Tetrabenazine is a drug for the...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Riluzole, a member of the benzothiazole class, is indicated for the treatment of patients with amyotrophic lateral sclerosis. Its pharmacological properties include the following, some of which may be related to its effect: 1) an inhibitory effect on...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Cysteamine (trade name CYSTAGON) is a cystine-depleting agent indicated for the treatment of corneal cystine crystal accumulation in patients with cystinosis. Cystinosis is an autosomal recessive inborn error of metabolism in which the transport of c...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Dronabinol also known as (−)-trans-delta9-tetrahydrocannabinol is an active ingredient of cannabis. The drug was approved by FDA for the treatment of anorexia in patients with AIDS and chemotherapy-induced nausea and vomiting. Dronabinol exerts its a...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Clotrimazole is an anti-fungal medicine indicated for the treatment of vaginal yeast infections and tinea. It can be used either in combination with other drugs (betamethasone dipropionate) or alone, in form of topical or vaginal cream. The drug exer...
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Selisistat (EX 527) was discovered by Elixir scientists as a selective human SIRT1 inhibitor and exhibits >200-fold selectivity against SIRT2 and SIRT3. Human SIRT1 is an enzyme that deacetylates the p53 tumor suppressor protein and has been sugge...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Carbenoxolone is a glycyrrhetinic acid derivative with a steroid-like structure, similar to substances found in the flavor-ful root of the licorice plant. It influences endogenous glucocorticoids by potently inhibiting 11β-hydroxysteroid dehydrogenas...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
UBIQUINOL is a reduced form of coenzyme Q10, a lipid-soluble molecule that consists of an aromatic ring and a 10-unit isoprenoid chain. It is naturally produced by the body. A significant increase in plasma CoQ10 status observed after supplementation...