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Details

Stereochemistry ACHIRAL
Molecular Formula C59H92O4
Molecular Weight 865.3616
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 9
Charge 0

SHOW SMILES / InChI
Structure of UBIQUINOL

SMILES

CC(=CCC/C(=C(\[H])/CC/C(=C(\[H])/CC/C(=C(\[H])/CC/C(=C(\[H])/CC/C(=C(\[H])/CC/C(=C(\[H])/CC/C(=C(\[H])/CC/C(=C(\[H])/CC/C(=C(\[H])/Cc1c(C)c(c(c(c1O)OC)OC)O)/C)/C)/C)/C)/C)/C)/C)/C)/C)C

InChI

InChIKey=QNTNKSLOFHEFPK-UPTCCGCDSA-N
InChI=1S/C59H92O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42,60-61H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

HIDE SMILES / InChI
UBIQUINOL is a reduced form of coenzyme Q10, a lipid-soluble molecule that consists of an aromatic ring and a 10-unit isoprenoid chain. It is naturally produced by the body. A significant increase in plasma CoQ10 status observed after supplementation in one study suggested that UBIQUINOL is a better supplemental form to enhance the CoQ10 status than ubiquinone (the oxidized form of Q10). UBIQUINOL has also been found to reduce oxidative stress induced by strenuous exercise. Oxidative stress is associated with aging and many chronic diseases, such as cardiovascular diseases, cancers, and cognitive decline. Ubiquinol has furthermore been shown to improve mitochondrial oxidative metabolism in the brain, and cognitive improvement was found as a result of Ubiquinol intake in chronic fatigue syndrome patients. UBIQUINOL is considered safe, but can have side effects such as upper abdominal pain, loss of appetite, nausea, diarrhea and headaches. CoQ10 might make blood-thinning drugs, such as warfarin (Coumadin, Jantoven), less effective. This could increase the risk of a blood clot.

Approval Year

Targets
Name Type Language
UBIQUINOL
INCI   USP-RS   WHO-DD  
INCI  
Official Name English
DIHYDROCOENZYME Q10
Common Name English
UBIQUINOL [USP-RS]
Common Name English
UBIQUINOL-10
Common Name English
REDUCED COENZYME Q10
Common Name English
1,4-BENZENEDIOL, 2-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-DECAMETHYL-2,6,10,14,18,22,26,30,34,38-TETRACONTADECAEN-1-YL)-5,6-DIMETHOXY-3-METHYL-
Common Name English
UBIQUINOL [INCI]
Common Name English
UBIQUINONE HYDROQUINONE
Common Name English
UBIQUINOL [WHO-DD]
Common Name English
Classification Tree Code System Code
EU-Orphan Drug EU/3/16/1765
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
FDA ORPHAN DRUG 179403
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
Code System Code Type Description
EVMPD
SUB32843
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY
PUBCHEM
9962735
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY
MESH
C026663
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY
FDA UNII
M9NL0C577Y
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY
WIKIPEDIA
UBIQUINOL
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY
DRUG BANK
DB11340
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY
USP_CATALOG
1705334
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY USP-RS
RXCUI
39085
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY RxNorm
CAS
992-78-9
Created by admin on Sat Jun 26 04:52:17 UTC 2021 , Edited by admin on Sat Jun 26 04:52:17 UTC 2021
PRIMARY