Nickel nitrate is the inorganic compound Ni(NO3)2. The most common form of nickel nitrate is hexahydrate. It is irritating to the eyes, skin and, upon inhalation of the dust, respiratory tract. It may cause skin allergy. Along with most other nickel compounds, nickel nitrate is a carcinogen. Nickel(II) nitrate hexahydrate is widely used in the production of nickel catalysts, by impregnating an inert carrier and decomposing the nitrate.

There is no information about biological and pharmacological application of lead stearate. But is known, that this is a toxic substance which can accumulate inside organism, because it can be absorbed through the skin.

Rosiglitazone acts as a highly selective and potent agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. It is FDA approved for the treatment of as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Inhibitors of CYP2C8 (e.g., gemfibrozil) may increase rosiglitazone levels; inducers of CYP2C8 (e.g., rifampin) may decrease rosiglitazone levels. Common adverse reactions include edema, weight gain, and headache.

There is no information about biological application only a few articles about pharmacological application of lead fluoride, that this substance was investigated for topical dental caries.