LEAD MONOXIDE

US Previously Marketed

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	O.Pb
Molecular Weight	225.2
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O--].[PbH2++]

InChI

InChIKey=MQZBBIXFDYLEGH-UHFFFAOYSA-N

InChI=1S/O.Pb.2H/q-2;+2;;

HIDE SMILES / InChI

Molecular Formula	Pb
Molecular Weight	209.2
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20340530 | https://www.ncbi.nlm.nih.gov/pubmed/18935555https://www.ncbi.nlm.nih.gov/pubmed/14038324http://nj.gov/health/eoh/rtkweb/documents/fs/1107.pdfhttps://www.ncbi.nlm.nih.gov/pubmed/27486358FRITZ BISCHOFF, L. C. MAXWELL, RICHARD D. EVANS, and FRANKLIN R. NUZUM. Journal of Pharmacology and Experimental Therapeutics September 1928, 34 (1) 85-109, retrived from http://jpet.aspetjournals.org/content/34/1/85 | https://www.ncbi.nlm.nih.gov/pubmed/14038324https://www.ncbi.nlm.nih.gov/pubmed/2535340
Curator's Comment: description was created based on several sources, including https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf

There is no information related to biological or pharmacological application of lead(II) bromide (a combustion product of the gasoline additives lead (IV) tetraethyl and 1,2-dibromoethane). It is only known, that this substance possesses mutagenicity.

CNS Activity

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596
Unknown 2596
Unknown 2596
Unknown 2596
Unknown 2596
Unknown 2596

PubMed

Title	Date	PubMed
Highly luminescent nanoscale quasi-2D layered lead bromide perovskites with tunable emissions.	2016-03-11	26853766
Rat Testis Damage Caused by Lead Sulfide Nanoparticles After Oral Exposure.	2016-03	27455644
Autophagy plays a protective role in cell death of osteoblasts exposure to lead chloride.	2015-12-03	26383630
Probit analysis of comparative assays on toxicities of lead chloride and lead acetate to in vitro cultured human umbilical cord blood lymphocytes.	2015-03	27486358
The oxidative damage and inflammatory response induced by lead sulfide nanoparticles in rat lung.	2013-10	23891762
Maternal low-level lead exposure reduces the expression of PSA-NCAM and the activity of sialyltransferase in the hippocampi of neonatal rat pups.	2008-07	18499259
[Lead in the blood and protoporphyrin levels in erythrocytes in glass workers exposed to lead].	1997-12	9721457
Structural Chemistry of Poly(ethylene glycol) Complexes of Lead(II) Nitrate and Lead(II) Bromide.	1996-11-20	11666874
[The late effects of exposure to lead fluoride].	1992-03	1427189
Mutagenic effects of lead (II) bromide.	1989-12	2535340
Lead oxide emissions--a case history.	1986	3752846
Interconnection of activation volumes and activation enthalpies in cubic lead fluoride doped with alkali-metal cations.	1985-06-15	9935786
Abiotic factors affecting the toxicity of lead to fungi.	1979-09	43707
Subacute effects of lead-oxide fumes in demolition workers.	1977-01-08	63652
Interaction of lead and bacterial lipids.	1975-05	1147606
Microbial uptake of lead.	1972-06-23	5034545
[Contribution to the study on allergy among workers exposed to lead oxide and lead sulfide].	1961-07-01	14038324
The effect of topical applications of lead fluoride on dental caries.	1947-12	18935555
The effect of topically applied fluorides on dental caries experience; report of findings with two, four and six applications of sodium fluoride and of lead fluoride.	1947-10-10	20340530

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Dental

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:04:01 GMT 2025` Edited by `admin` on `Mon Mar 31 18:04:01 GMT 2025`
Record UNII	4IN6FN8492
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LEAD MONOXIDE

Systematic Name

English

NSC-57634

Preferred Name

English

LEAD MONOXIDE [MI]

Common Name

English

PLUMBOUS OXIDE

Common Name

English

Lead monoxide [WHO-DD]

Common Name

English

MASSICOT

Common Name

English

LITHARGE

Common Name

English

LEAD OXIDE [HSDB]

Common Name

English

LEAD MONOXIDE [VANDF]

Common Name

English

LEAD(II) OXIDE

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

48002