Suncillin is an antibacteria and antifungal agent produced in Phytera's laboratory from a cell culture of a plant. Suncillin was patented by Bristol-Myers Co. In 1968 for the Pseudomonas bacteria treatment but was never marketed.

Cypenamine (2-phenylcyclopentylamine) is a psychostimulant and antidepressant drug developed at William S. Merrell Chemical Company.

Americium is a radioactive metallic element with atomic number 95 and element symbol Am. It's the only synthetic element encountered in everyday life, in minute quantities in ionization-type smoke detectors. Americium was first synthesized and identified in 1944 by Glenn T. Seaborg, Ralph James, L Morgan, and Albert Ghiorso at the University of California, Berkeley as part of the Manhattan Project. The element was produced using a 60-inch cyclotron. Americium is a shiny silver radioactive metal. All isotopes of this element are radioactive. The isotope with the longest half-life is americium-243, which has a half-life of 7370 years. The most common isotopes are americium-241, with a half-life of 432.7 years, and americium-243. Americium-242 is also known, with a half-life of 141 years. In total, 19 isotopes and 8 nuclear isomers have been characterized. The isotopes variously undergo alpha, beta, and gamma decay. EPA Facts AboutAmericium-241EPA Facts About Americium-241 July 2002 What is americium-241? Americium is a man-made radioactive metal that exists as a solid under normal conditions. Americium is produced when plutonium absorbs neutrons in nuclear reactors and nuclear weapons tests. Americium occurs in several forms called isotopes. The most common isotope is americium-241. Americium when blended with beryllium is used as a neutron source in the testing of machinery and in thickness gauges in the glass industry. Americium also is used as a radiation source in medical diagnostic devices and in research. Possible uses are in medicine where gamma emission of Am-241 has allowed the deter-mination of mineral content of bones, lipid content of soft tissues, and body composition. Americium is commonly used in minute amounts in smoke detectors as an ionization source. However this isotope is extremely expensive to produce in usable quantities. There is no known biological role of americium in living organisms. It's generally considered toxic because of its radioactivity.

Iodophthalein was used as an iodine-containing X-ray contrast agent in icteric subjects. There is also existed mention, that iodophthalein has also been used as a wound treatment, and for the treatment of intestinal catarrhs. But nowadays more modern drugs are being used.

Dexsotalol is an isomer of antiarrhythmic drug d,l-sotalol, but in opposite to drug, it increases the incidence of arrhythmias

HDAC-IN-2 (also known as citarinostat or ACY-241) was developed as a selective histone deacetylase (HDAC) 6 inhibitor with potential antineoplastic activity. Inhibition of HDAC leads to the inhibition of tumor oncogene transcription, and the selective transcription of tumor suppressor genes, which inhibit tumor cell division and induce tumor cell apoptosis. HDAC-IN-2 participates in phase 1b clinical trial in patients with multiple myeloma to determine the maximum tolerated dose (MTD) and evaluate the safety and preliminary antitumor activity. Besides, HDAC-IN-2 in combination with paclitaxel participates in phase Ib in patients with advanced solid tumors. In addition, HDAC-IN-2 in combination with nivolumab participates in phase I in patients with unresectable non-small cell lung cancer to determine the safety, tolerability, dose-limiting toxicities (DLTs), and maximum tolerated dose (MTD) of the drug.