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Details

Stereochemistry ACHIRAL
Molecular Formula C20H18F3N7O2
Molecular Weight 445.3978
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACRIZANIB

SMILES

CNCC1=CC(OC2=CC=C3N(C=CC3=C2)C(=O)NC4=NN(C)C(=C4)C(F)(F)F)=NC=N1

InChI

InChIKey=XPIHPLVWOUDMPF-UHFFFAOYSA-N
InChI=1S/C20H18F3N7O2/c1-24-10-13-8-18(26-11-25-13)32-14-3-4-15-12(7-14)5-6-30(15)19(31)27-17-9-16(20(21,22)23)29(2)28-17/h3-9,11,24H,10H2,1-2H3,(H,27,28,31)

HIDE SMILES / InChI

Molecular Formula C20H18F3N7O2
Molecular Weight 445.3978
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Fri Dec 15 19:13:36 GMT 2023
Edited
by admin
on Fri Dec 15 19:13:36 GMT 2023
Record UNII
F2CB8801I3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ACRIZANIB
INN  
INN  
Official Name English
1H-INDOLE-1-CARBOXAMIDE, 5-((6-((METHYLAMINO)METHYL)-4-PYRIMIDINYL)OXY)-N-(1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-YL)-
Systematic Name English
5-((6-((METHYLAMINO)METHYL)PYRIMIDIN-4-YL)OXY)-N-(1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-YL)-1H-INDOLE-1-CARBOXAMIDE
Systematic Name English
LHA510
Code English
LHA-510
Code English
acrizanib [INN]
Common Name English
Code System Code Type Description
SMS_ID
300000034119
Created by admin on Fri Dec 15 19:13:36 GMT 2023 , Edited by admin on Fri Dec 15 19:13:36 GMT 2023
PRIMARY
CAS
1229453-99-9
Created by admin on Fri Dec 15 19:13:36 GMT 2023 , Edited by admin on Fri Dec 15 19:13:36 GMT 2023
PRIMARY
NCI_THESAURUS
C169761
Created by admin on Fri Dec 15 19:13:36 GMT 2023 , Edited by admin on Fri Dec 15 19:13:36 GMT 2023
PRIMARY
FDA UNII
F2CB8801I3
Created by admin on Fri Dec 15 19:13:36 GMT 2023 , Edited by admin on Fri Dec 15 19:13:36 GMT 2023
PRIMARY
PUBCHEM
59394698
Created by admin on Fri Dec 15 19:13:36 GMT 2023 , Edited by admin on Fri Dec 15 19:13:36 GMT 2023
PRIMARY
INN
10448
Created by admin on Fri Dec 15 19:13:36 GMT 2023 , Edited by admin on Fri Dec 15 19:13:36 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET -> INHIBITOR
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ACTIVE MOIETY