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Restrict the search for
testosterone propionate
to a specific field?
Status:
Investigational
Source:
Oncology. 2005;69(1):19-26.: Phase 3 Human clinical trial Completed Lymphoma, Non-Hodgkin/pathology
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Quiflapon Sodium (MK-0591; (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid, previously L-686,708) had been in phase II clinical studies for the treatment of inflammatory bowel disease, but the study was discontinued later, because in spite of MK-591 markedly inhibited Leukotrienes (LT) biosynthesis, it did not differ significantly from placebo in clinical efficacy. Also was discovered, that MK-0591 may modify the airway changes associated with bronchial hyper responsiveness, as well as offer symptomatic relief in asthma. MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay. In additional, recently was discovered, that MK591 possesses all major attributes of a standard anti-metastatic agent with significant cancer-selective effect, and suggest that MK591 may turn out to be an effective agent for therapy of castration-resistant, bone-metastatic prostate cancer. Though details of the molecular underpinnings of the anti-metastatic action of MK591 are unknown at this time, this finding gives an opportunity for further exploration to better understand the signaling mechanisms involved by in vitro and in vivo experiments.
Status:
Investigational
Source:
INN:proxifezone [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Proxifezone is a mixture of phenylbutazone and d-propoxyphene patented by Societe d'Etudes de Recherches et d'Applications Scientifiques et Medicales E.R.A.S.M.E. as an anti-inflammation pharmaceutical composition with potent analgesic activity. Anti-inflammatory effects of Proxifezone associated with Phenylbutazone, that acts as a nonsteroidal anti-inflammatory drug (NSAID). D-propoxyphene acts as an opioid analgesic, that provides strong pain relief.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
TS-410 (Amelometasone), is a topical anti-inflammatory steroid. Amelometasone lotion - external steroid preparation - is marketed in Japan.
Class (Stereo):
CHEMICAL (RACEMIC)
Butaverine is a fatty acid ester with antispasmodic activity which was under development for treatment urinary incontinence
Class (Stereo):
CHEMICAL (ABSOLUTE)
Orestrate was developed as an estrogenic steroid that has never been marketed.
Status:
Investigational
Source:
USAN:ROSARAMICIN PROPIONATE [USAN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
Eur J Heart Fail. Oct 2022;24(10):1967-1977.: Phase 2 Human clinical trial Completed Shock, Cardiogenic/etiology
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Etiocholanone is an androstane neurosteroid. Etiocholanone potentiates GABA-A receptor currents and exerts anticolvunsant properties in rodents. Etiocholanolone demostrates pyrogenic properties.
Class (Stereo):
CHEMICAL (RACEMIC)
Lonaprofen is an analgesic, antipyretic and anti-inflammatory agent.
Status:
Investigational
Source:
INN:dexproxibutene [INN]
Source URL:
Class (Stereo):
CHEMICAL (UNKNOWN)
Dexproxibutene is an experimental agent structurally related to propoxyphene. It is an analgesic agent. Dexproxibutene is not very effective in rheumatoid arthritis pain relief. It is intermediate in effectiveness between distalgesic, codis, aspirin and placebo.
