TICABESONE PROPIONATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H32F2O5S
Molecular Weight	482.58
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@@H](C)[C@](OC(=O)CC)(C(=O)SC)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])C[C@H](F)C4=CC(=O)C=C[C@]34C

InChI

InChIKey=DRXCUKXWTNOXTD-CENSZEJFSA-N

InChI=1S/C25H32F2O5S/c1-6-20(30)32-25(21(31)33-5)13(2)9-15-16-11-18(26)17-10-14(28)7-8-22(17,3)24(16,27)19(29)12-23(15,25)4/h7-8,10,13,15-16,18-19,29H,6,9,11-12H2,1-5H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2410194 | https://www.ncbi.nlm.nih.gov/pubmed/22000935

Ticabesone Propionate is Ticabesone ester patented by Syntex, Inc. as an anti-inflammatory agent. Ticabesone Propionate shows potent antiinflammatory activity silver nitrate-induced inflammation in the rat cornea.

Originator

Approval Year

PubMed

Title	Date	PubMed
Drug effects on the neovascularization response to silver nitrate cauterization of the rat cornea.	1985 May	2410194

Patents

Name

Type

Language

TICABESONE PROPIONATE

Official Name

English

FLUTICASONE PROPIONATE IMPURITY D [EP IMPURITY]

Common Name

English

RS-35909-00-00-0

Code

English

S-METHYL 6.ALPHA.,9.ALPHA.-DIFLUORO-11.BETA.-HYDROXY-16.ALPHA.-METHYL-3-OXO-17.ALPHA.-PROPIONYLOXY-ANDROSTA-1,4-DIENE-17.BETA.-CARBOTHIOATE

Common Name

English

FLUTICASONE PROPIONATE RELATED COMPOUND D [USP IMPURITY]

Common Name

English

6.ALPHA.,9-DIFLUORO-17-((METHYLSULFANYL)CARBONYL)-11.BETA.-HYDROXY-16.ALPHA.-METHYL-3-OXOANDROSTA-1,4-DIEN-17.ALPHA.-YL PROPANOATE

Common Name

English

ANDROSTA-1,4-DIENE-17-CARBOTHIOIC ACID, 6,9-DIFLUORO-11-HYDROXY-16-METHYL-3-OXO-17-(1-OXOPROPOXY)-, S-METHYL ESTER, (6.ALPHA.,11.BETA.,16.ALPHA.,17.ALPHA.)-

Common Name

English

FLUTICASONE PROPIONATE RELATED COMPOUND D [USP-RS]

Common Name

English

TICABESONE PROPIONATE [USAN]

Common Name

English

FLUTICASONE PROPIONATE RELATED COMPOUND D

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521