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474
Possibly Marketed Outside US
14
US Approved Rx
4
Investigational
3
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Primary Target
Prostaglandin F2-alpha receptor
4
Prostanoid FP receptor
4
Muscarinic acetylcholine receptor M1
3
Toll-like receptor 4
2
5-hydroxytryptamine receptor 1A
1
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Highest Phase
Approved
7
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Approval Year
Unknown
482
1995
4
2009
2
2013
2
1982
1
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Condition
Unknown
6
Ocular hypertension
4
Open-angle glaucoma
4
Cutaneous leishmaniasis
3
Lung adenocarcinoma
1
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Treatment Modality
Primary
5
Curative
4
Palliative
4
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CNS Activity
CNS Penetrant
1
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Originator
NicOx
4
Roszowski, A.P.
2
AstraZeneca
1
Deville, S.C.
1
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Substance Class
Chemical
458
Protein
22
Polymer
10
Structurally Diverse
2
Concept
1
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INN Stem
Chemical substance(-ine)
3
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Code System
FDA UNII
493
CAS
453
PUBCHEM
452
EPA CompTox
373
ECHA (EC/EINECS)
211
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Protein Type
PEPTIDE
5
CYTOKINE
1
ENZYME
1
PREPROTEIN
1
STRUCTURAL PROTEIN
1
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ATC Level 1
DERMATOLOGICALS
1
SENSORY ORGANS
1
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ATC Level 2
ANTIFUNGALS FOR DERMATOLOGICAL USE
1
OPHTHALMOLOGICALS
1
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ATC Level 3
ANTIFUNGALS FOR TOPICAL USE
1
ANTIGLAUCOMA PREPARATIONS AND MIOTICS
1
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ATC Level 4
Other antifungals for topical use
1
Prostaglandin analogues
1
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Substance Form
Principal Form
464
Salts, Hydrates, Esters, etc.
29
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