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474
Possibly Marketed Outside US
14
US Approved Rx
4
Investigational
3
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Primary Target
Prostaglandin F2-alpha receptor
4
Prostanoid FP receptor
4
Muscarinic acetylcholine receptor M1
3
Toll-like receptor 4
2
5-hydroxytryptamine receptor 1A
1
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Highest Phase
Approved
7
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Approval Year
Unknown
482
1995
4
2009
2
2013
2
1982
1
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Condition
Unknown
6
Ocular hypertension
4
Open-angle glaucoma
4
Cutaneous leishmaniasis
3
Lung adenocarcinoma
1
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Treatment Modality
Primary
5
Curative
4
Palliative
4
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CNS Activity
CNS Penetrant
1
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Originator
NicOx
4
Roszowski, A.P.
2
AstraZeneca
1
Deville, S.C.
1
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Substance Class
Chemical
458
Protein
22
Polymer
10
Structurally Diverse
2
Concept
1
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INN Stem
Chemical substance(-ine)
3
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Code System
FDA UNII
493
CAS
453
PUBCHEM
452
EPA CompTox
373
ECHA (EC/EINECS)
211
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Protein Type
PEPTIDE
5
CYTOKINE
1
ENZYME
1
PREPROTEIN
1
STRUCTURAL PROTEIN
1
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ATC Level 1
DERMATOLOGICALS
1
SENSORY ORGANS
1
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ATC Level 2
ANTIFUNGALS FOR DERMATOLOGICAL USE
1
OPHTHALMOLOGICALS
1
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ATC Level 3
ANTIFUNGALS FOR TOPICAL USE
1
ANTIGLAUCOMA PREPARATIONS AND MIOTICS
1
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ATC Level 4
Other antifungals for topical use
1
Prostaglandin analogues
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Substance Form
Principal Form
464
Salts, Hydrates, Esters, etc.
29
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4,4'-[Ethylenebis[iminosulfonyl(6-methoxy-m-phenylene)azo]]bis[5'-chloro-3-hydroxy-2',4'-dimethoxynaphth-2-anilide]
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KW2P2B345W
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
1-((4-(m-Tolyl)-4-piperidyl)carbonyl)pyrrolidine
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GY6L4GG5Z9
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CHEMICAL (ACHIRAL)
m-Hydroxybenzyl acetate
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TSQ4QET8K4
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Class (Stereo):
CHEMICAL (ACHIRAL)
2-Amino-4-chloro-5-sulfamyl-N-(m-tolyl)benzamide
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F6L2G59Z89
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Class (Stereo):
CHEMICAL (ACHIRAL)
DAROLUTAMIDE METABOLITE M-32
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B62K64WQ32
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Class (Stereo):
CHEMICAL (EPIMERIC)
Crisaborole m-isomer
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RY5P9BKG47
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Class (Stereo):
CHEMICAL (ACHIRAL)
N-(4-AMINO-M-TOLYL)-N-ETHYLBENZAMIDE
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MPN8KT4ERS
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Class (Stereo):
CHEMICAL (ACHIRAL)
CIMIRACEMOSIDE M
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A3XBG3EN6B
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Class (Stereo):
CHEMICAL (ABSOLUTE)
M-(BENZYLOXY)TOLUENE
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3ELF78FA8T
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Class (Stereo):
CHEMICAL (ACHIRAL)
M-METHYLCINNAMIC ACID
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377B8288XF
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Class (Stereo):
CHEMICAL (ACHIRAL)
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