U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 38101 - 38110 of 39591 results

Status:
US Previously Marketed
Source:
Cerium Oxalate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Cerium Oxalate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cerous iodide is a salt of lanthanide metal cerium (III) and iodide ion. In 1920s solution of cerous iodide for intravenous injection (called "introcid") was used as an antimicrobial agent for treating puerperal fever. It has shown prophylactic activity against sepsis, and was explored for its antineoplastic properties in patients with lymphogranulomatosis or inoperable solid tumors. According to the clinical reports, it has been applied with remarkable benefit, as indicated by tumor shrinkage and improved quality of life in several cases of locally advanced or metastatic tumors of different origin.
Status:
US Previously Marketed
Source:
Solution of Lead Subacetate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Solution of Lead Subacetate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Lead(II) acetate is a white crystalline chemical compound with a sweetish taste. Lead(II) acetate is used as a mordant in textile printing and dyeing, as a drier in paints and varnishes, and in preparing other lead compounds. It was historically used as a sweetener and for cosmetics.
Status:
US Previously Marketed
Source:
SPARTASE POTASSIUM ASPARTATE by WYETH
(1961)
Source URL:
First marketed in 1921
Source:
potassium aspartate
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Disodium aspartate is used in organic biosynthesis.
Status:
US Previously Marketed
Source:
Nitric Acid U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Nitric Acid U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Nitrate ion (NO3 −) is found naturally in the environment and is an important plant nutrient. It is present at varying concentrations in all plants and is a part of the nitrogen cycle. Nitrate probably has a role in protecting the gastrointestinal tract against a variety of gastrointestinal pathogens, as nitrous oxide and acidified nitrite have antibacterial properties. Significant bacterial reduction of nitrate to nitrite does not normally take place in the stomach, except in individuals with low gastric acidity or with gastrointestinal infections. These may include individuals using antacids, particularly those that block acid secretion. Potassium nitrate is used as mild local desensitizer in toothpastes.
Status:
US Previously Marketed
Source:
Corrosive Mercuric Chloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Corrosive Mercuric Chloride U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Potassium Triiodomercurate(II) is a periodometallate salt. It contains a triiodomercurate(1-). It is an antiseptic (topical) and disinfectant. It is also an antiseborrheic agent.
Status:
US Previously Marketed
Source:
Sodium Borate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sodium Borate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

BORATE, a salt of boric acid, is used as a food additive in the European Union. This additive is authorized for use as preservatives of sturgeon eggs (caviar).
Status:
US Previously Marketed
Source:
Zinc Valerate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Zinc Valerate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Valeric acid is a colorless, oily liquid with an unpleasant odor. It is highly corrosive and must be handled with care. Valeric acid is mainly used as a chemical intermediate to manufacture flavors and perfumes, synthetic lubricants, agricultural chemicals, and pharmaceuticals. It is also used as a flavoring aid in foods. Valeric acid is considered safe as a food additive by the World Health Organization.
Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and handling of silver iodide stem from its toxicologic properties. Effects from exposure may include skin rashes, conjunctivitis, argyria (a permanent ashen-gray discoloration of skin, conjunctiva, and internal organs), headache, fever, hypersensitivity, laryngitis, and bronchitis.
Status:
US Previously Marketed
Source:
Antimony Oxide N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Antimony Oxide N.F.
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)



Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.
Gallic acid is a polyphenol found in a variety of foods and herbs. Several studies have shown thta gallic acid has neuroprotective and anti-oxidant properties and can be a promising candidate for the treatment of cancer, cardiovascular diseases, neurodegenerative disorders, fatty liver disease and many others. Gallic acid acts by protecting cells against oxidative damage caused by reactive species often encountered in biological systems including, hydroxyl, superoxide and peroxyl and the non-radicals, hydrogen peroxide and hypochlorous acid. However, its ability to induce apoptosis, is mainly associated with its prooxidant, rather than antioxidant behavior.

Showing 38101 - 38110 of 39591 results