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Search results for "Pharmacologic Substance[C1909]|Hormone Therapy Agent[C147908]|Therapeutic Hormone[C548]" in comments (approximate match)
Status:
US Previously Marketed
Source:
GEREF by EMD SERONO
(1990)
Source URL:
First approved in 1990
Source:
GEREF by EMD SERONO
Source URL:
Class:
PROTEIN
Conditions:
Sermorelin, a 29 amino acid analog of human growth hormone-releasing hormone (GHRH), is the shortest synthetic peptide with a full biological activity of GHRH which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. Intravenous and subcutaneous sermorelin specifically stimulate growth hormone secretion from the anterior pituitary. Sermorelin binds to the growth hormone releasing hormone receptor and mimics native GRF in its ability to stimulate growth hormone secretion. Hormone responses to intravenous sermorelin appear to be a rapid and relatively specific test for the diagnosis of growth hormone deficiency.
Status:
US Previously Marketed
Source:
CIBACALCIN by NOVARTIS
(1986)
Source URL:
First approved in 1986
Source:
CIBACALCIN by NOVARTIS
Source URL:
Class:
PROTEIN
Status:
First approved in 1985
Class:
PROTEIN
Status:
US Previously Marketed
First approved in 1978
Class:
PROTEIN
Seractide is a polypeptide hormone corresponding to thirty-nine amino acids of human corticotropin that differs from full-length human corticotropin at four positions. Seractide is potent endogenous melanocortin receptor 2 (MC ) agonist. Seractide stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). Seractide, was approved by FDA in 1978, but was never marketed. The Seractide, that was ultimately withdrawn by FDA in 2014 for safety reasons.
Status:
US Previously Marketed
Source:
DIAPID by NOVARTIS
(1970)
Source URL:
First approved in 1970
Source:
DIAPID by NOVARTIS
Source URL:
Class:
PROTEIN
Targets:
Conditions:
Lypressin is synthetic analog of porcine antidiuretic hormone vasopressin. Itis a cyclic nonapeptide that differs from Arg-vasopressin by one amino acid, containing Lys at residue 8 instead of Arg. Lypressin-containing nasal spray was used to treat diabetes insipidus, but its marketing by Sandoz (Novartis) was discontinued.
Status:
First approved in 1950
Class:
PROTEIN
Conditions:
Insulin Pork is Insulin isolated from pig pancreas. Insulin is a hormone secreted by the beta cells of the pancreas to help move glucose from the blood into body cells for energy. People with Type 1 diabetes lose the ability to produce insulin and must inject it. In the past, all commercially available insulin came from the pancreases of cows or pigs. Pork and beef insulins are similar to human insulin, differing only in one or a few amino acids. However, even a slight difference is enough to elicit an allergic response in some people. To overcome this problem, researchers looked for ways to make insulin that would more closely resemble human insulin.
Status:
Possibly Marketed Outside US
Source:
NADA140872
(2011)
Source URL:
First approved in 2011
Source:
NADA140872
Source URL:
Class:
PROTEIN
Status:
Possibly Marketed Outside US
Source:
NCT04236115: Phase 4 Interventional Completed Overcoming the Failure of Anaesthesia
(2017)
Source URL:
Class:
PROTEIN
Targets:
Conditions:
Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. Felypressin is added to some local anesthetics such as prilocaine in a concentration of 0.03 IU/ml. Its antidiuretic effects are less than those of vasopressin. Felypressin is used as a vasoconstrictor in local anesthetic injections for dental use and is an ingredient of preparations that have been used for the treatment of pain and inflammation of the mouth.
Status:
Possibly Marketed Outside US
Source:
NCT00220987: Phase 4 Interventional Completed Hyperglycemia
(2005)
Source URL:
Class:
PROTEIN