SERMORELIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Previously Marketed

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18031173 | https://www.ncbi.nlm.nih.gov/pubmed/18046908 | https://www.ncbi.nlm.nih.gov/pubmed/2429796

Sermorelin, a 29 amino acid analog of human growth hormone-releasing hormone (GHRH), is the shortest synthetic peptide with a full biological activity of GHRH which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. Intravenous and subcutaneous sermorelin specifically stimulate growth hormone secretion from the anterior pituitary. Sermorelin binds to the growth hormone releasing hormone receptor and mimics native GRF in its ability to stimulate growth hormone secretion. Hormone responses to intravenous sermorelin appear to be a rapid and relatively specific test for the diagnosis of growth hormone deficiency.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
growth hormone deficiency 2 Sources: https://www.drugs.com/cons/geref.html	Diagnostic		Approved 8429	GEREF Approved Use Diagnosing and treating growth hormone deficiency in children Launch Date 6.623424E11

Sample Use Guides

In Vivo Use Guide

1 mcg/kg bodyweight

Route of Administration: Intravenous

Substance Class	Protein Created by `admin` on `Sat Dec 16 00:28:23 UTC 2023` Edited by `admin` on `Sat Dec 16 00:28:23 UTC 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	89243S03TE
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SERMORELIN

Official Name

English

sermorelin [INN]

Common Name

English

Sermorelin [WHO-DD]

Common Name

English

SERMORELIN [MI]

Common Name

English

SERMORELIN [VANDF]

Common Name

English

GROWTH HORMONE-RELEASING FACTOR (HUMAN)-(1-29)-PEPTIDE AMIDE RECOMBINANT

Common Name

English

TYR-ALA-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-NH2

Common Name

English

GROLIBERIN

Brand Name

English

Classification Tree Code System Code

WHO-VATC

QH01AC04

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

WHO-ATC

H01AC04

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

NCI_THESAURUS

C76358

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

WHO-VATC

QV04CD03

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

WIKIPEDIA

Designer-drugs-Sermorelin

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

WHO-ATC

V04CD03

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

Code System Code Type Description

FDA UNII

89243S03TE

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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DRUG BANK

DB00010

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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DRUG CENTRAL

2433

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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CAS

86168-78-7

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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EPA CompTox

DTXSID70903978

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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CHEBI

9118

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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NCI_THESAURUS

C62088

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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RXCUI

56188

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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RxNorm

WIKIPEDIA

Sermorelin

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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IUPHAR

6998

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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EVMPD

SUB10496MIG

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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PUBCHEM

16132413

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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INN

6036

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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MERCK INDEX

m9870

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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Merck Index

MESH

D017337

Created by admin on Sat Dec 16 00:28:23 UTC 2023 , Edited by admin on Sat Dec 16 00:28:23 UTC 2023

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Related Record Type Details


					89243S03TE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:SEQUENCE(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL