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Development Status
US Approved Rx
106
Possibly Marketed Outside US
85
Investigational
69
Other
39
US Previously Marketed
34
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Primary Target
Adrenergic receptor alpha-1
40
Adrenergic receptor alpha-2
38
Adrenergic receptor alpha
23
Alpha-1a adrenergic receptor
20
Alpha-1b adrenergic receptor
16
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Highest Phase
Approved
180
Phase III
6
Phase II
5
Phase I
4
Not Provided
2
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Approval Year
Unknown
164
1921
11
1996
10
1954
7
1987
7
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Condition
Hypertension
34
Benign prostatic hyperplasia
13
Unknown
12
Pain
9
Nasal congestion
8
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Treatment Modality
Primary
174
Palliative
30
Preventing
27
Curative
17
Diagnostic
9
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CNS Activity
CNS Active
66
CNS Penetrant
63
CNS Non-penetrant
20
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Originator
Pfizer
10
Abbott Laboratories
4
Bayer
4
Roche
4
Abbott
3
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Substance Class
Chemical
317
Protein
31
Mixture
8
Polymer
6
Structurally Diverse
2
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Code System
FDA UNII
364
CAS
352
PUBCHEM
318
NCI_THESAURUS
315
EPA CompTox
301
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Protein Type
MONOCLONAL ANTIBODY
8
CYTOKINE
4
ENZYME INHIBITOR
2
ENZYME
1
RECEPTOR
1
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ATC Level 1
CARDIOVASCULAR SYSTEM
39
ALIMENTARY TRACT AND METABOLISM
20
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
18
RESPIRATORY SYSTEM
16
GENITO URINARY SYSTEM AND SEX HORMONES
13
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ATC Level 2
NASAL PREPARATIONS
15
CARDIAC THERAPY
14
OPHTHALMOLOGICALS
13
ANTIHYPERTENSIVES
12
IMMUNOSTIMULANTS
9
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ATC Level 3
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
14
CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
12
IMMUNOSTIMULANTS
9
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
9
PERIPHERAL VASODILATORS
9
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ATC Level 4
Adrenergic and dopaminergic agents
12
Alpha-adrenoreceptor antagonists
12
Sympathomimetics, plain
12
Enzymes
7
Interferons
7
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Substance Form
Principal Form
242
Salts, Hydrates, Esters, etc.
122
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Search results for
alpha root_codes_comments
in
comments
(approximate match)
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