U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 3111 - 3120 of 3518 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

4-Piperidinol, 1-phenethyl-4-phenyl acetate (PEPAP) is a synthetic opioid discovered by Janssen in 1960. PEPAP is an analog of meperidine, it is abused and illegally sold on streets as a "synthetic heroin".
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

SB-206606 (better known as BRL-37344) was developed by Beecham Pharmaceuticals and is currently licensable from GlaxoSmithKline. SB-206606 is an agonist for the Beta-3 adrenergic receptor with an EC 50 value of 17 nM (human B3AR expressed in CHO cells). SB-206606 was in pre-clinical development as a potential treatment of Diabetes Mellitus, although such efforts have been discontinued. Recently it has also garnered some interest as a potential treatment for alcoholism.

Showing 3111 - 3120 of 3518 results