Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C11H10N4.C2H4O2 |
| Molecular Weight | 258.2759 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(O)=O.CC1=CC=CN2C1=NC3=C2N=C(N)C=C3
InChI
InChIKey=KMDUEQJDDOLNTJ-UHFFFAOYSA-N
InChI=1S/C11H10N4.C2H4O2/c1-7-3-2-6-15-10(7)13-8-4-5-9(12)14-11(8)15;1-2(3)4/h2-6H,1H3,(H2,12,14);1H3,(H,3,4)
| Molecular Formula | C2H4O2 |
| Molecular Weight | 60.052 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C11H10N4 |
| Molecular Weight | 198.2239 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Copper, zinc-superoxide dismutase enhances the mutagenicity in Salmonella typhimurium induced by 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole. | 2008-05-31 |
|
| A novel gender-related difference in the constitutive expression of hepatic cytochrome P4501A subfamily enzymes in Meishan pigs. | 2008-03-01 |
|
| Differential effects of heterocyclic amines on poly(ADP-ribose) polymerase-1 and mono-ADP-ribosyltransferase A. | 2006-09 |
|
| Chemical synthesis of 2'-deoxyguanosine-C8 adducts with heterocyclic amines: an application to synthesis of oligonucleotides site-specifically adducted with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | 2006-06 |
|
| In vitro antimutagenicity of capsaicin toward heterocyclic amines in Salmonella typhimurium strain TA98. | 2005-04-09 |
|
| Antigenotoxic properties of Cassia tea (Cassia tora L.): mechanism of action and the influence of roasting process. | 2004-11-19 |
|
| Inhibitory effects of beer on heterocyclic amine-induced mutagenesis and PhIP-induced aberrant crypt foci in rat colon. | 2004-04-11 |
|
| Functional characterization of four allelic variants of human cytochrome P450 1A2. | 2004-02-01 |
|
| Possibility of the involvement of 9H-pyrido[3,4-b]indole (norharman) in carcinogenesis via inhibition of cytochrome P450-related activities and intercalation to DNA. | 2003-11-10 |
|
| Inhibition of mutagenicity of food-derived heterocyclic amines by sulforaphane--a constituent of broccoli. | 2003-03 |
|
| Inhibitory effect of dibenzoylmethane on mutagenicity of food-derived heterocyclic amine mutagens. | 2003 |
|
| Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food. | 2002-12 |
|
| Antimutagenicity of Murdannia loriformis in the Salmonella mutation assay and its inhibitory effects on azoxymethane-induced DNA methylation and aberrant crypt focus formation in male F344 rats. | 2002-02 |
|
| Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). | 1995-12 |
|
| Genetic alterations in HCA-induced tumors. | 1995 |
|
| Absence of p53 mutations in rat colon tumors induced by 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole, 2-amino-3-methylimidazo[4,5-f]quinoline, or 2-amino-1-methyl-6-phenylimidazo]4,5-b]pyridine. | 1994-05 |
|
| Rare frequency of activation of the Ki-ras gene in rat colon tumors induced by heterocyclic amines: possible alternative mechanisms of human colon carcinogenesis. | 1993 |
|
| Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. | 1989-06-15 |
|
| Carcinogenicity in mice and rats of heterocyclic amines in cooked foods. | 1986-08 |
|
| Metabolic aspects of pyrolysis mutagens in food. | 1986-08 |
| Substance Class |
Chemical
Created
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admin
on
Edited
Mon Mar 31 23:37:16 GMT 2025
by
admin
on
Mon Mar 31 23:37:16 GMT 2025
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| Record UNII |
MYO77SM6OU
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| Record Status |
Validated (UNII)
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| Record Version |
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122418-95-5
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MYO77SM6OU
Created by
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SALT/SOLVATE -> PARENT |
