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Restrict the search for
dutasteride
to a specific field?
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2012)
Source URL:
First approved in 2012
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
ANDA074612
(1999)
Source URL:
First approved in 1999
Source:
ANDA074612
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Toluene is a colorless, water-insoluble liquid with the smell associated with paint thinners. It is a mono-substituted benzene derivative, consisting of a CH3 group attached to a phenyl group. The major use of toluene is as a mixture added to gasoline to improve octane ratings. Toluene is also usedto produce benzene and as a solvent in paints, coatings, synthetic fragrances, adhesives, inks, and cleaningagents. Toluene is also used in the production of polymers used to make nylon, plastic soda bottles, andpolyurethanes and for pharmaceuticals, dyes, cosmetic nail products, and the synthesis of organicchemicals. The CNS is the primary target organ for toluene toxicity in both humans and animals for acute and chronicexposures. CNS dysfunction (which is often reversible) and narcosis have been frequently observed inhumans acutely exposed to low or moderate levels of toluene by inhalation; symptoms include fatigue,sleepiness, headaches, and nausea. CNS depression and death have occurred at higher levels of exposure. Toluene is used in veterinary medicine as a treatment for various parasites in dogs and cats. It is used for the removal of ascarids (Toxocara canis and Toxascaris leonina) and hookworms (Ancylostoma caninum and Uncinaria stenocephala) and as an aid in removing tapeworms (Taenia pisiformis, Dipylidium caninum, and Echinococcus granulosus) from dogs and cats.
Status:
Possibly Marketed Outside US
Source:
21 CFR 348
(2020)
Source URL:
First approved in 1968
Source:
ANDA077154
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Heptane (or n-heptane) is used in laboratories as a non-polar solvent. Recently published article describes the biological monitoring of the n-heptane exposure by its metabolite concentrations and the time course of metabolite excretion.
Status:
Possibly Marketed Outside US
First approved in 1964
Source:
Stop-A-Leak by H. W. Naylor Company Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Ethyl acetate is a widely used synthetic solvent. It is used in cosmetics and considered to be safe. Ethyl acetate is cited as a direct and indirect food additive as detailed in the Code of Federal Regulations. Ethyl acetate is generally recognized as safe (GRAS) for use as a synthetic flavor and/or adjuvant; limitations on concentrations of use were not specified. Ethyl acetate was tested for in vitro in human breast cancer cell line and demonstrated considerable cytotoxicity.
Status:
Possibly Marketed Outside US
Source:
Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]
Source URL:
First approved in 2013
Source:
BLA125416
Source URL:
Class:
MIXTURE
